ID   Y077_MYCPN              Reviewed;         546 AA.
AC   P75040;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 2.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Major facilitator superfamily transporter MPN_077;
GN   OrderedLocusNames=MPN_077; ORFNames=MP078, R02_orf469;
OS   Mycoplasma pneumoniae (strain ATCC 29342 / M129) (Mycoplasmoides
OS   pneumoniae).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=272634;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29342 / M129;
RX   PubMed=8948633; DOI=10.1093/nar/24.22.4420;
RA   Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.;
RT   "Complete sequence analysis of the genome of the bacterium Mycoplasma
RT   pneumoniae.";
RL   Nucleic Acids Res. 24:4420-4449(1996).
RN   [2]
RP   SEQUENCE REVISION.
RC   STRAIN=ATCC 29342 / M129;
RX   PubMed=10954595; DOI=10.1093/nar/28.17.3278;
RA   Dandekar T., Huynen M., Regula J.T., Ueberle B., Zimmermann C.U.,
RA   Andrade M.A., Doerks T., Sanchez-Pulido L., Snel B., Suyama M., Yuan Y.P.,
RA   Herrmann R., Bork P.;
RT   "Re-annotating the Mycoplasma pneumoniae genome sequence: adding value,
RT   function and reading frames.";
RL   Nucleic Acids Res. 28:3278-3288(2000).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000305}.
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DR   EMBL; U00089; AAG34737.1; -; Genomic_DNA.
DR   PIR; S73404; S73404.
DR   RefSeq; NP_109765.1; NC_000912.1.
DR   RefSeq; WP_010874434.1; NC_000912.1.
DR   AlphaFoldDB; P75040; -.
DR   STRING; 272634.MPN_077; -.
DR   EnsemblBacteria; AAG34737; AAG34737; MPN_077.
DR   KEGG; mpn:MPN_077; -.
DR   PATRIC; fig|272634.6.peg.78; -.
DR   HOGENOM; CLU_033053_0_0_14; -.
DR   OMA; IYDKKRW; -.
DR   BioCyc; MPNE272634:G1GJ3-118-MON; -.
DR   Proteomes; UP000000808; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR011699; MFS_Mycoplasma.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07672; MFS_Mycoplasma; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..546
FT                   /note="Major facilitator superfamily transporter MPN_077"
FT                   /id="PRO_0000210406"
FT   TRANSMEM        2..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        88..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        179..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        220..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        248..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        305..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        344..364
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        377..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        401..421
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        442..462
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        485..505
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   546 AA;  60148 MW;  7238E3F1E51468D3 CRC64;
     MWGLVLLGYV LFVIEWFVID FIRGSAASLL TEQTSAVPQY GGWFSSFFVA DAGFIPGQAT
     NWTITLLRAV GSILCGVMVV KFGYRHAVMI MMGLMCVCFP FLIIGSPLGG HNELTLLRPA
     SSEVISKLTK ISSSLQQGQL LGPVQVGSQT MLADGTPVSL IKGINGNEIG TSASMTGYAF
     FIIFRSTIAI GGTTLIAYAQ PIIASLSSNR KKSILSNANF WGFNVGLVIV AAPFLIPGVG
     RFATANWVWV VTFMILLVFA MLLVFAWFEK KVDHMLPQKQ SKTNQSLSVR PSALSILKRK
     TTWKLLAIAG VGTILLINPL TQTWFNSLLA ISGAKKAIIP TARPILLILW VMGYLLGYFL
     LSPFNKTIYD KKRWLHFIFT ANAVLVLLIV IFAATLGLNT VVGFTFVGIF TFIAGGFGWS
     LGSSILILPY EYKEYKRNEV SIIFGYVWGF AYVFYSIFDI ITSVFLDAPR IATGNTSANI
     LPGAIAAIVL FVSLLLVINW VIIYLPSSWI KNGDECVSEM TKKWRITQWQ FLIANKAKNR
     YADLLK