ID   Y078_MYCSJ              Reviewed;         312 AA.
AC   A3PSL4;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase Mjls_0078;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=Mjls_0078;
OS   Mycobacterium sp. (strain JLS).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; unclassified Mycobacterium.
OX   NCBI_TaxID=164757;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JLS;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Anderson A.J.,
RA   Sims R.C., Richardson P.;
RT   "Complete sequence of Mycobacterium sp. JLS.";
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000580; ABN95891.1; -; Genomic_DNA.
DR   AlphaFoldDB; A3PSL4; -.
DR   SMR; A3PSL4; -.
DR   STRING; 164757.Mjls_0078; -.
DR   KEGG; mjl:Mjls_0078; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; PMDITEL; -.
DR   BioCyc; MSP164757:G1G8C-83-MON; -.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..312
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase Mjls_0078"
FT                   /id="PRO_0000361201"
FT   BINDING         134
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         163..164
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   312 AA;  34450 MW;  74FEB2AE19134E20 CRC64;
     MSSLRTADDT WDIATSVGST AVMVAASRAA ETERDEALIR DPYARLLVTG AGTGIWESVL
     DAKFVETVAA ADAEAAAIFE HMNSYQAVRT HFFDAFFTAA AEAGIRQIVI LASGLDSRAY
     RLDWPSGTTV YEIDQPKVLE YKSATLAEHG VEPVATRREV GIDLRHDWPA ALRGAGFDPS
     RPTAWLAEGL LMYLPADAQD RLFEQITELS APGSRVAAET AGVQAEDRRQ QMRERFERIA
     EKFDMTASLD IQQLIYEDPD RADVADWLDA HGWTATAVSS QQEMRRLDRW ALPADLTDDD
     AFSNFVTAEK LS