ID   Y084_STAAC              Reviewed;         745 AA.
AC   Q5HJR8;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 2.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator SACOL0084;
GN   OrderedLocusNames=SACOL0084;
OS   Staphylococcus aureus (strain COL).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93062;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=COL;
RX   PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA   Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA   Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA   Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA   Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA   Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA   Fraser C.M.;
RT   "Insights on evolution of virulence and resistance from the complete genome
RT   analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT   a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT   strain.";
RL   J. Bacteriol. 187:2426-2438(2005).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAW38728.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000046; AAW38728.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_001188495.1; NC_002951.2.
DR   AlphaFoldDB; Q5HJR8; -.
DR   SMR; Q5HJR8; -.
DR   EnsemblBacteria; AAW38728; AAW38728; SACOL0084.
DR   KEGG; sac:SACOL0084; -.
DR   HOGENOM; CLU_017624_1_0_9; -.
DR   Proteomes; UP000000530; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR037923; HTH-like.
DR   InterPro; IPR018060; HTH_AraC.
DR   InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR   Pfam; PF12833; HTH_18; 1.
DR   PRINTS; PR00032; HTHARAC.
DR   SMART; SM00342; HTH_ARAC; 1.
DR   SUPFAM; SSF46689; SSF46689; 2.
DR   SUPFAM; SSF51215; SSF51215; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE   4: Predicted;
KW   DNA-binding; Repeat; Transcription; Transcription regulation.
FT   CHAIN           1..745
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   SACOL0084"
FT                   /id="PRO_0000194627"
FT   DOMAIN          158..256
FT                   /note="HTH araC/xylS-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        175..196
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        223..246
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
SQ   SEQUENCE   745 AA;  87957 MW;  AF50232A926CD576 CRC64;
     MQRDYLIRVE TESMSDFKRL NSLMIGFVIK GEAHIYDENN MTQCNSGDIF IINHRDLYRF
     QLQQDGIICY IQFQMKYLAD KFDDVHCLYF HLTDATTTKN IHQLRNIMAR LVSTHIRHNE
     LSKLTEQQLV IQLLMHMIHY VPRTYHSNQS ILNDDKVNQV CDYIELHFHE DLSLSELSEY
     VGWSESHLSK KFTESLGVGF HHFLNTTRIE HAKLDLTYTD ETITDIALQN GFSSAASFAR
     TFKHFTHQTP KQYRGDRPAI TENQQSAQHD YHDRELILLL NDYIEEMNHF IEDIEKMNYK
     EIAFQPTNHQ LNQFNHIIQV GYLRNLLNTQ YQSQLLTCHH DFQVNEVLAY DVIPYIMKKL
     NAPFTYDAEI SNIFYDIDLC LDFLLDHNFS LTMHLDQYDS RDYIDAFKIF IHHVALHVSH
     RKDLKFNLYV TTLHTSLIEM IDYFKALFPN GGLYIHLDQA TERHLPLLKR LEPHIDHFVF
     DANSNDAVDF NKMNDDEFKT ASQMIINKTN YLIDLMHRHR LKRPLILLNW NTLTGDTFIT
     NGEYFRGGII IEQLLKLSSK VEGIGYWLNY DLHVSHCKNE RDYMNSIELF HQYNGKRPVY
     FTALLFNKLT SNILYSDDTC IVTGTDSNFQ ILLYDAKHFN PYLALDNQMN MRATEMIHLN
     INALEEGMYK IKHFTLDKEN GALFNLWRKH HTIHGMDKDS IDYVNRMSFP KLEVYDIDIT
     DTLALNIKMI TNGIHLIEVK RYPSS