ID   CAPP_MYCA1              Reviewed;         935 AA.
AC   A0QHY0;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000255|HAMAP-Rule:MF_00595};
DE            Short=PEPC {ECO:0000255|HAMAP-Rule:MF_00595};
DE            Short=PEPCase {ECO:0000255|HAMAP-Rule:MF_00595};
DE            EC=4.1.1.31 {ECO:0000255|HAMAP-Rule:MF_00595};
GN   Name=ppc {ECO:0000255|HAMAP-Rule:MF_00595}; OrderedLocusNames=MAV_3336;
OS   Mycobacterium avium (strain 104).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=243243;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=104;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC       for the tricarboxylic acid cycle. {ECO:0000255|HAMAP-Rule:MF_00595}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC         phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00595};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00595};
CC   -!- SIMILARITY: Belongs to the PEPCase type 1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00595}.
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DR   EMBL; CP000479; ABK67960.1; -; Genomic_DNA.
DR   RefSeq; WP_011725407.1; NC_008595.1.
DR   AlphaFoldDB; A0QHY0; -.
DR   SMR; A0QHY0; -.
DR   EnsemblBacteria; ABK67960; ABK67960; MAV_3336.
DR   KEGG; mav:MAV_3336; -.
DR   HOGENOM; CLU_006557_2_0_11; -.
DR   OMA; PWVFGWT; -.
DR   OrthoDB; 398146at2; -.
DR   Proteomes; UP000001574; Chromosome.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   PANTHER; PTHR30523; PTHR30523; 1.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; SSF51621; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation; Lyase; Magnesium.
FT   CHAIN           1..935
FT                   /note="Phosphoenolpyruvate carboxylase"
FT                   /id="PRO_1000025565"
FT   ACT_SITE        161
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00595"
FT   ACT_SITE        593
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00595"
SQ   SEQUENCE   935 AA;  102548 MW;  DF4E7779B3A41F2B CRC64;
     MVEASEGTLE PIGAVQRTLV GREATEPMRA DIGLLGAILG DTVREQNGQQ VFELVERARV
     ESFRVRRSEI DRAELARMFA GIDIHQAIPV IRAFSHFALL ANVAEDIHRE RRRAIHVAAG
     EPPQDSSLAA TYAKLDRAQL DSATVAEALR GAVVSPVITA HPTETRRRTV FVTQHRITEL
     MRLHAEGHIE TDDGRNIELE LRRQVLTLWQ TALIRLSRLQ ITDEIEVGLR YYAAAFFKVI
     PRVNAEVRNA LRARWPGADL LDEPIVAPGS WIGGDRDGNP NVTADVVRRA TGDAAYTALA
     HYLAELTACE QELSMSARLV AVTPELAALA EDCAEKARAD EPYRRALRVI RGRLTATAAE
     ILDRRPQHEL DLGLPPYATP AELRGDLDTV DASLRAHGSA LLADDRLALL REGVRVFGFH
     LCGLDMRQNS DVHEEVVAEL LAWAGVHPDY RSLPEDERVE LLAAELGTRR PLVGDRAELS
     ELADKELGVV RAAAHAIRRY GPAAVPNYVI SMCRSVSDVL EAAILLKEAG LIDASGPEPY
     CPVGISPLFE TIEDLHNGAA ILHAMLELPL YRALVAARGQ SQEVMLGYSD SNKDGGYLAS
     SWAVYRAELA LVEVARKTGI RLRLFHGRGG TVGRGGGPSY EAILAQPPGA VNGSLRLTEQ
     GEVIAAKYAE PQVAQRNLES LVAATLESTL LDVEGLGDTA EPAYAVLDEV AVLAQRAYAE
     LVHETPGFVD YFMASTPVSE IGSLNIGSRP TSRKPTESIA DLRAIPWVLA WSQSRVMLPG
     WYGTGSAFEQ WIAAGPQSRA ERVDILHDLY RRWPFFRSVL SNLAQVLAKS DLGLAAQYAE
     LVDDAALRRR VFGKIADEHR RTIAMHKLIT GQDNLLADNP ALARSVFNRF PYLEPLNHLQ
     VELLRRYRSG DDDELVQRGI LLTMNGLTSA LRNSG