ID   Y088_NEIMB              Reviewed;         466 AA.
AC   Q9K1M2;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Putative outer membrane protein NMB0088;
DE   Flags: Precursor;
GN   OrderedLocusNames=NMB0088;
OS   Neisseria meningitidis serogroup B (strain MC58).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=122586;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MC58;
RX   PubMed=10710307; DOI=10.1126/science.287.5459.1809;
RA   Tettelin H., Saunders N.J., Heidelberg J.F., Jeffries A.C., Nelson K.E.,
RA   Eisen J.A., Ketchum K.A., Hood D.W., Peden J.F., Dodson R.J., Nelson W.C.,
RA   Gwinn M.L., DeBoy R.T., Peterson J.D., Hickey E.K., Haft D.H.,
RA   Salzberg S.L., White O., Fleischmann R.D., Dougherty B.A., Mason T.M.,
RA   Ciecko A., Parksey D.S., Blair E., Cittone H., Clark E.B., Cotton M.D.,
RA   Utterback T.R., Khouri H.M., Qin H., Vamathevan J.J., Gill J., Scarlato V.,
RA   Masignani V., Pizza M., Grandi G., Sun L., Smith H.O., Fraser C.M.,
RA   Moxon E.R., Rappuoli R., Venter J.C.;
RT   "Complete genome sequence of Neisseria meningitidis serogroup B strain
RT   MC58.";
RL   Science 287:1809-1815(2000).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=17038831; DOI=10.4161/hv.1.2.1651;
RA   Vipond C., Wheeler J.X., Jones C., Feavers I.M., Suker J.;
RT   "Characterization of the protein content of a meningococcal outer membrane
RT   vesicle vaccine by polyacrylamide gel electrophoresis and mass
RT   spectrometry.";
RL   Hum. Vaccin. 1:80-84(2005).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=NZ98/254 / Serogroup B;
RX   PubMed=16645985; DOI=10.1002/pmic.200500821;
RA   Vipond C., Suker J., Jones C., Tang C., Feavers I.M., Wheeler J.X.;
RT   "Proteomic analysis of a meningococcal outer membrane vesicle vaccine
RT   prepared from the group B strain NZ98/254.";
RL   Proteomics 6:3400-3413(2006).
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- MISCELLANEOUS: Present in outer membrane vesicle formulations which are
CC       used as vaccines in human.
CC   -!- SIMILARITY: Belongs to the OmpP1/FadL family. {ECO:0000305}.
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DR   EMBL; AE002098; AAF40551.1; -; Genomic_DNA.
DR   PIR; A81239; A81239.
DR   RefSeq; NP_273150.1; NC_003112.2.
DR   RefSeq; WP_002221819.1; NC_003112.2.
DR   AlphaFoldDB; Q9K1M2; -.
DR   SMR; Q9K1M2; -.
DR   STRING; 122586.NMB0088; -.
DR   PaxDb; Q9K1M2; -.
DR   EnsemblBacteria; AAF40551; AAF40551; NMB0088.
DR   KEGG; nme:NMB0088; -.
DR   PATRIC; fig|122586.8.peg.125; -.
DR   HOGENOM; CLU_035981_0_1_4; -.
DR   OMA; NRYGFTY; -.
DR   Proteomes; UP000000425; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015483; F:long-chain fatty acid transporting porin activity; IBA:GO_Central.
DR   InterPro; IPR005017; OMPP1/FadL/TodX.
DR   PANTHER; PTHR35093; PTHR35093; 1.
DR   Pfam; PF03349; Toluene_X; 1.
PE   1: Evidence at protein level;
KW   Cell outer membrane; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane beta strand.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..466
FT                   /note="Putative outer membrane protein NMB0088"
FT                   /id="PRO_0000349890"
SQ   SEQUENCE   466 AA;  50518 MW;  878A5B34A8646609 CRC64;
     MTPSALKKTV LLLGTAFAAA SVHASGYHFG TQSVNAQSTA NAAAAEAADA STIFYNPAGL
     TKLDSSQISV NANIVLPSIH YEADSATDFT GLPVQGSKSG KITKTTVAPH IYGAYKVNDN
     LTVGLGVYVP FGSATEYEKD SVLRHNINKL GLTSIAVEPV AAWKLNDRHS FGAGIIAQHT
     SAELRKYADW GIKSKAEILT AKPPKPNGVA EAAKIQADGH ADVKGSDWGF GYQLAWMWDI
     NDRARVGVNY RSKVSHTLKG DAEWAADGAA AKAMWSTMLA ANGYTANEKA RVKIVTPESL
     SVHGMYKVSD KADLFGDVTW TRHSRFDKAE LVFEKEKTVV KGKSDRTTIT PNWRNTYKVG
     FGGSYQISEP LQLRAGIAFD KSPVRNADYR MNSLPDGNRI WFSAGMKYHI GKNHVVDAAY
     THIHINDTSY RTAKASGNDV DSKGASSARF KNHADIIGLQ YTYKFK