ID   Y089_RICFE              Reviewed;        1138 AA.
AC   Q4UNB8;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Uncharacterized protein RF_0089;
DE   Flags: Precursor;
GN   OrderedLocusNames=RF_0089;
OS   Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=315456;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-1525 / URRWXCal2;
RX   PubMed=15984913; DOI=10.1371/journal.pbio.0030248;
RA   Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E.,
RA   Parinello H., Claverie J.-M., Raoult D.;
RT   "The genome sequence of Rickettsia felis identifies the first putative
RT   conjugative plasmid in an obligate intracellular parasite.";
RL   PLoS Biol. 3:1-12(2005).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TrbL/VirB6 family. {ECO:0000305}.
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DR   EMBL; CP000053; AAY60940.1; -; Genomic_DNA.
DR   RefSeq; WP_011270443.1; NC_007109.1.
DR   AlphaFoldDB; Q4UNB8; -.
DR   STRING; 315456.RF_0089; -.
DR   EnsemblBacteria; AAY60940; AAY60940; RF_0089.
DR   KEGG; rfe:RF_0089; -.
DR   eggNOG; COG3704; Bacteria.
DR   HOGENOM; CLU_279905_0_0_5; -.
DR   OMA; WVKLMIS; -.
DR   OrthoDB; 11886at2; -.
DR   Proteomes; UP000008548; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030255; P:protein secretion by the type IV secretion system; IEA:InterPro.
DR   InterPro; IPR007688; Conjugal_tfr_TrbL/VirB6.
DR   Pfam; PF04610; TrbL; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..1138
FT                   /note="Uncharacterized protein RF_0089"
FT                   /id="PRO_0000269204"
FT   TRANSMEM        331..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        359..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        392..412
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        494..514
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        520..540
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        554..574
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        699..719
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          775..914
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          958..977
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          995..1071
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        800..834
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        850..874
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        875..892
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        995..1036
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1037..1052
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1138 AA;  124823 MW;  3078D631C0DFAF94 CRC64;
     MKLFPRSILI ILVLSFALNL GLVTKTHAKD TLDSIVDILS GLTCETQGVG DLLRTEFSHT
     CIVAPFFTFA VMNLVSPVLY MNTFLKLKIN DSDLFNDSNF GNFPGGQCTR ENRIDPKNPE
     LRFALCNNAK LIVSRAKSVA ESALAIAKAV LTGGDPWDDI KKAWENKKKE YHIPYSGKPG
     DDGFAFDAGF PVIYWKIIQD KDRICVSTKG FTGDVPVGCK YMKEPFPKSM YNSFMDVADK
     DFIQDPKETP TDPLALVSCS AAGGGCYQKA YNASKTAVVM TSPLIECMRQ MIARLLISKD
     VCSFDNVEQV VNLASRQDSA LFQFQVGMYK IVTAFLTLYV MFFGFKLLLA GEIPPKSEYI
     NFILKMIFVT YFSIGINITP GNGSPYDRLD GMIQWAFPFL LDGINGLASW VMNAAPSGLC
     KFNNLSYDGT VSYIALWDAL DCRVAHYLGL DILSTLLVEN AYRSHDFLNF DFFSFSAPPY
     IYLLIPAIIS GNMMLVSLAL SYPLLVISVA AFMVNATIMC MISIVILGIL APLFVPMFLF
     TYTRNYFDSW VKLMISFLLQ PMVVVTFMIT MFSVYDYGFY GKCQYKSKLI HNSIENLAQS
     GGTSSRDVLI FYINNDWDDI SQYPDKDAVE SCQNSLGYML NNPITTAFNF AKDSVSEIVD
     SKPGDTPTDK FLAKFQFLSG VVLGPGMFFM SPKVLFEKIK NILLALVTAC FTLYLMYNFS
     SQLAEFAADM TEGVALNNVA IKPQAIFKAG MAALAAAGAA TKGVDQIASR GGVGDLKAGQ
     GGGVSDNIAK SGGGGPNDNI AASGGTSAPT VTTPTASSSV ATSSPKTVSS EARSDVVTPP
     PAPSEAVSPP PASIRTSIST PAPQSNIETE SVGKIIRDNN QESKKEIDNT PPPQEKVDNA
     APQEKVDSTS KGTGVIDYSF NLKEHENPAG VKQIRENAEI RDKRAEVEKA WNELVASGGG
     RIRDQQGEET SERRTNAEKK WNELVDSGVV TEIRERDNSV TNKFDKLADE LNKSEKAKVE
     ENKNIENDRK ENNTTTSPQE KVDSTSRGSG VIDYSFNLKE HENPTGVKQI RENAEIRDKR
     VKVETAWNEL VASGGGRVRE QEGGEVSERR ANAVKTWDEL VKSGVVTEKK DNSSNENS