Y091_CAUVC
ID Y091_CAUVC Reviewed; 809 AA.
AC Q9ABX9;
DT 10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Uncharacterized signaling protein CC_0091;
GN OrderedLocusNames=CC_0091;
OS Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=190650;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19089 / CB15;
RX PubMed=11259647; DOI=10.1073/pnas.061029298;
RA Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R.,
RA Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B.,
RA DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F.,
RA Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R.,
RA Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O.,
RA Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M.;
RT "Complete genome sequence of Caulobacter crescentus.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000255|PROSITE-ProRule:PRU00244}.
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DR EMBL; AE005673; AAK22078.1; -; Genomic_DNA.
DR PIR; B87260; B87260.
DR RefSeq; NP_418910.1; NC_002696.2.
DR RefSeq; WP_010917980.1; NC_002696.2.
DR PDB; 4YME; X-ray; 1.40 A; A=372-528.
DR PDBsum; 4YME; -.
DR AlphaFoldDB; Q9ABX9; -.
DR SMR; Q9ABX9; -.
DR STRING; 190650.CC_0091; -.
DR EnsemblBacteria; AAK22078; AAK22078; CC_0091.
DR KEGG; ccr:CC_0091; -.
DR PATRIC; fig|190650.5.peg.88; -.
DR eggNOG; COG3300; Bacteria.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_49_5; -.
DR OMA; RMVMTTS; -.
DR BioCyc; CAULO:CC0091-MON; -.
DR Proteomes; UP000001816; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.20.20.450; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR005330; MHYT_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF03707; MHYT; 2.
DR Pfam; PF13188; PAS_8; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; SSF141868; 1.
DR SUPFAM; SSF55073; SSF55073; 1.
DR SUPFAM; SSF55785; SSF55785; 1.
DR TIGRFAMs; TIGR00254; GGDEF; 1.
DR TIGRFAMs; TIGR00229; sensory_box; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50924; MHYT; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..809
FT /note="Uncharacterized signaling protein CC_0091"
FT /id="PRO_0000170473"
FT TRANSMEM 23..43
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00244"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00244"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00244"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00244"
FT TRANSMEM 152..172
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00244"
FT TRANSMEM 186..206
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00244"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00244"
FT DOMAIN 19..206
FT /note="MHYT"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00244"
FT DOMAIN 254..317
FT /note="PAS"
FT DOMAIN 402..536
FT /note="GGDEF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00095"
FT DOMAIN 545..795
FT /note="EAL"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00074"
FT TURN 376..378
FT /evidence="ECO:0007829|PDB:4YME"
FT STRAND 379..381
FT /evidence="ECO:0007829|PDB:4YME"
FT HELIX 383..400
FT /evidence="ECO:0007829|PDB:4YME"
FT STRAND 403..411
FT /evidence="ECO:0007829|PDB:4YME"
FT HELIX 414..421
FT /evidence="ECO:0007829|PDB:4YME"
FT HELIX 423..440
FT /evidence="ECO:0007829|PDB:4YME"
FT STRAND 445..451
FT /evidence="ECO:0007829|PDB:4YME"
FT STRAND 454..461
FT /evidence="ECO:0007829|PDB:4YME"
FT HELIX 465..479
FT /evidence="ECO:0007829|PDB:4YME"
FT STRAND 484..486
FT /evidence="ECO:0007829|PDB:4YME"
FT STRAND 489..491
FT /evidence="ECO:0007829|PDB:4YME"
FT STRAND 495..501
FT /evidence="ECO:0007829|PDB:4YME"
FT TURN 502..505
FT /evidence="ECO:0007829|PDB:4YME"
FT HELIX 509..526
FT /evidence="ECO:0007829|PDB:4YME"
SQ SEQUENCE 809 AA; 86879 MW; 4BCF69414372113E CRC64;
MTLKERCVFK LLTCLTTQHD LRLVLVASAV CLAGCFTTFR LYSRMRGARG VVRAAWLLLT
GLVAGSSVWA THFIAMVAFT PGLKTGYSPT GTLLSLMIAA LFMASGFAVA SAQRSTTNDF
AGGVLIGLGV AAMHYMGMSA FVTQGQLVWE HATVGMSAVL GVGGATAALL LAGTARTIRR
QAVGGGMLCL GIVMLHFTGM SAITIVPDAS LTVPDQLLSG GMLTLAVGSI TSMIILGGLG
AVAIESQTSR SALERIRRLA NAAYEGLVVV QSGRINDANA AFCDLVGAPL AELVGRPLFG
EILTFDEADP SREDVRREGR LRPLVGGREI PVEVFSRLMD DGARVETSGL TVLAVRDLRE
RRAAEEKIRY LAEHDGLTGL LNRNSLQMRL AAAIDRVEAS GESLAVICID LDHFKEANDQ
HGHLAGDALL VETARRLQSA VQAPSFAARL GGDEFIVVQI AGGDQPAVAA ELAGRLIEML
AAPVPFDGQE LAMGSSLGVS LYPDDGRTAE ALMANADMAL YRAKESGRGV YRFFKREMDD
TIRERRNLAR DLRQGIADNE LIVHYQPLAR AADGEVCGFE ALVRWKHPTR GMIPPLDFIP
VAEENGLIEA LGDWVLRRAC ADAAAWEKPL RIAVNLSPIQ LHNPALPTLV HEVLITTGLS
PSRLELEITE SALFKDYQRA LDNLRRLKAL GVRIAMDDFG TGFSSLSTLQ SFPFDKIKID
KSFVENIHRH DRATAIVRAV LGLGRSLEIP VVAEGVETEE QILFLRGEDC AELQGYAIGR
PAPVDALTMW TTAGDPGAIA PKSKTRRSA
