Y091_METJA
ID Y091_METJA Reviewed; 302 AA.
AC Q57556;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 25-MAY-2022, entry version 122.
DE RecName: Full=Uncharacterized membrane protein MJ0091;
GN OrderedLocusNames=MJ0091;
OS Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS 10045 / NBRC 100440) (Methanococcus jannaschii).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanocaldococcus.
OX NCBI_TaxID=243232;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT jannaschii.";
RL Science 273:1058-1073(1996).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19)
CC family. {ECO:0000305}.
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DR EMBL; L77117; AAB98072.1; -; Genomic_DNA.
DR PIR; C64311; C64311.
DR RefSeq; WP_010869583.1; NC_000909.1.
DR PDB; 3V5S; X-ray; 3.50 A; A=1-302.
DR PDB; 3V5U; X-ray; 1.90 A; A=1-302.
DR PDB; 5HWX; X-ray; 2.40 A; A=1-301.
DR PDB; 5HWY; X-ray; 2.10 A; A=1-300.
DR PDB; 5HXC; X-ray; 2.10 A; A=1-302.
DR PDB; 5HXE; X-ray; 2.29 A; A=1-302.
DR PDB; 5HXH; X-ray; 2.80 A; A/B=1-300.
DR PDB; 5HXR; X-ray; 2.46 A; A=1-300.
DR PDB; 5HXS; X-ray; 2.79 A; A=1-300.
DR PDB; 5HYA; X-ray; 1.90 A; A=1-302.
DR PDB; 5JDF; X-ray; 2.65 A; A=1-302.
DR PDB; 5JDG; X-ray; 2.41 A; A=1-302.
DR PDB; 5JDH; X-ray; 2.20 A; A=1-301.
DR PDB; 5JDL; X-ray; 2.90 A; A=1-301.
DR PDB; 5JDM; X-ray; 2.56 A; A=1-302.
DR PDB; 5JDN; X-ray; 2.30 A; A=1-302.
DR PDB; 5JDQ; X-ray; 2.50 A; A=1-302.
DR PDBsum; 3V5S; -.
DR PDBsum; 3V5U; -.
DR PDBsum; 5HWX; -.
DR PDBsum; 5HWY; -.
DR PDBsum; 5HXC; -.
DR PDBsum; 5HXE; -.
DR PDBsum; 5HXH; -.
DR PDBsum; 5HXR; -.
DR PDBsum; 5HXS; -.
DR PDBsum; 5HYA; -.
DR PDBsum; 5JDF; -.
DR PDBsum; 5JDG; -.
DR PDBsum; 5JDH; -.
DR PDBsum; 5JDL; -.
DR PDBsum; 5JDM; -.
DR PDBsum; 5JDN; -.
DR PDBsum; 5JDQ; -.
DR AlphaFoldDB; Q57556; -.
DR SMR; Q57556; -.
DR STRING; 243232.MJ_0091; -.
DR TCDB; 2.A.19.5.3; the ca(2+):cation antiporter (caca) family.
DR DNASU; 1450930; -.
DR EnsemblBacteria; AAB98072; AAB98072; MJ_0091.
DR GeneID; 1450930; -.
DR KEGG; mja:MJ_0091; -.
DR eggNOG; arCOG02881; Archaea.
DR HOGENOM; CLU_007948_0_1_2; -.
DR InParanoid; Q57556; -.
DR OMA; TRDYGVM; -.
DR OrthoDB; 45269at2157; -.
DR PhylomeDB; Q57556; -.
DR Proteomes; UP000000805; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0005262; F:calcium channel activity; IBA:GO_Central.
DR GO; GO:0008273; F:calcium, potassium:sodium antiporter activity; IBA:GO_Central.
DR GO; GO:0070588; P:calcium ion transmembrane transport; IBA:GO_Central.
DR GO; GO:0006874; P:cellular calcium ion homeostasis; IBA:GO_Central.
DR Gene3D; 1.20.1420.30; -; 1.
DR InterPro; IPR004481; K/Na/Ca-exchanger.
DR InterPro; IPR004837; NaCa_Exmemb.
DR InterPro; IPR044880; NCX_ion-bd_dom_sf.
DR PANTHER; PTHR10846; PTHR10846; 2.
DR Pfam; PF01699; Na_Ca_ex; 2.
DR TIGRFAMs; TIGR00367; TIGR00367; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..302
FT /note="Uncharacterized membrane protein MJ0091"
FT /id="PRO_0000209509"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 106..126
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 163..183
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 227..247
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 254..274
FT /note="Helical"
FT /evidence="ECO:0000255"
FT HELIX 2..33
FT /evidence="ECO:0007829|PDB:5HYA"
FT HELIX 38..43
FT /evidence="ECO:0007829|PDB:5HYA"
FT HELIX 45..63
FT /evidence="ECO:0007829|PDB:5HYA"
FT HELIX 67..83
FT /evidence="ECO:0007829|PDB:5HYA"
FT HELIX 85..92
FT /evidence="ECO:0007829|PDB:5HYA"
FT HELIX 99..118
FT /evidence="ECO:0007829|PDB:5HYA"
FT TURN 119..121
FT /evidence="ECO:0007829|PDB:5HYA"
FT HELIX 125..145
FT /evidence="ECO:0007829|PDB:5HYA"
FT HELIX 153..155
FT /evidence="ECO:0007829|PDB:5HWY"
FT HELIX 159..192
FT /evidence="ECO:0007829|PDB:5HYA"
FT HELIX 198..203
FT /evidence="ECO:0007829|PDB:5HYA"
FT HELIX 205..209
FT /evidence="ECO:0007829|PDB:5HYA"
FT HELIX 211..222
FT /evidence="ECO:0007829|PDB:5HYA"
FT HELIX 226..242
FT /evidence="ECO:0007829|PDB:5HYA"
FT HELIX 244..251
FT /evidence="ECO:0007829|PDB:5HYA"
FT HELIX 258..277
FT /evidence="ECO:0007829|PDB:5HYA"
FT HELIX 282..298
FT /evidence="ECO:0007829|PDB:5HYA"
SQ SEQUENCE 302 AA; 32213 MW; 3D4F8373ED375879 CRC64;
MLILGVGYFL LGLILLYYGS DWFVLGSERI ARHFNVSNFV IGATVMAIGT SLPEILTSAY
ASYMHAPGIS IGNAIGSCIC NIGLVLGLSA IISPIIVDKN LQKNILVYLL FVIFAAVIGI
DGFSWIDGVV LLILFIIYLR WTVKNGSAEI EENNDKNNPS VVFSLVLLII GLIGVLVGAE
LFVDGAKKIA LALDISDKVI GFTLVAFGTS LPELMVSLAA AKRNLGGMVL GNVIGSNIAD
IGGALAVGSL FMHLPAENVQ MAVLVIMSLL LYLFAKYSKI GRWQGILFLA LYIIAIASLR
MG
