ID   Y095_MYCBP              Reviewed;         979 AA.
AC   A1KEN2;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=UPF0182 protein BCG_0095 {ECO:0000255|HAMAP-Rule:MF_01600};
GN   OrderedLocusNames=BCG_0095;
OS   Mycobacterium bovis (strain BCG / Pasteur 1173P2).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=410289;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BCG / Pasteur 1173P2;
RX   PubMed=17372194; DOI=10.1073/pnas.0700869104;
RA   Brosch R., Gordon S.V., Garnier T., Eiglmeier K., Frigui W., Valenti P.,
RA   Dos Santos S., Duthoy S., Lacroix C., Garcia-Pelayo C., Inwald J.K.,
RA   Golby P., Garcia J.N., Hewinson R.G., Behr M.A., Quail M.A., Churcher C.,
RA   Barrell B.G., Parkhill J., Cole S.T.;
RT   "Genome plasticity of BCG and impact on vaccine efficacy.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:5596-5601(2007).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01600};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01600}.
CC   -!- SIMILARITY: Belongs to the UPF0182 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01600}.
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DR   EMBL; AM408590; CAL70079.1; -; Genomic_DNA.
DR   RefSeq; WP_003901785.1; NC_008769.1.
DR   AlphaFoldDB; A1KEN2; -.
DR   PRIDE; A1KEN2; -.
DR   KEGG; mbb:BCG_0095; -.
DR   HOGENOM; CLU_007733_1_0_11; -.
DR   OMA; HFRYPLD; -.
DR   Proteomes; UP000001472; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01600; UPF0182; 1.
DR   InterPro; IPR005372; UPF0182.
DR   PANTHER; PTHR39344; PTHR39344; 1.
DR   Pfam; PF03699; UPF0182; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..979
FT                   /note="UPF0182 protein BCG_0095"
FT                   /id="PRO_0000291282"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        114..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        174..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        260..280
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        288..308
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   REGION          898..948
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        916..946
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   979 AA;  107417 MW;  9A46157009536CBD CRC64;
     METGSPGKRP VLPKRARLLV TAGMGMLALL LFGPRLVDIY VDWLWFGEVG FRSVWITVLL
     TRLAIVAAVA LVVAGIVLAA LLLAYRSRPF FVPDEPQRDP VAPLRSAVMR RPRLFGWGIA
     VTLGVVCGLI ASFDWVKVQL FVHGGTFGIV DPEFGYDIGF FVFDLPFYRS VLNWLFVAVV
     LAFLASLLTH YLFGGLRLTT GRGMLTQAAR VQLAVFAGAV VLLKAVAYWL DRYELLSSGR
     KEPTFTGAGY TDIHAELPAK LVLVAIAVLC AVSFFTAIFL RDLRIPAMAA ALLVLSAILV
     GGLWPLLMEQ FSVRPNAADV ERPYIQRNIE ATREAYRIGG DWVQYRSYPG IGTKQPRDVP
     VDVTTIAKVR LLDPHILSRT FTQQQQLKNF FSFAEILDID RYRIDGELQD YIVGVRELSP
     KSLTGNQTDW INKHTVYTHG NGFVAAPANR VNAAARDAEN ISDSNSGYPI YAVSDIASLG
     SGRQVIPVEQ PRVYYGEVIA QADPDYAIVG GAPGSAPREY DTDTSKYTYT GAGGVSIGNW
     FNRTVFATKF AQHKFLFSRE IGSESKVLIH RDPKERVQRV APWLTTDDNP YPVVVNGRIV
     WIVDAYTTLD TYPYAQRSSL EGPVTSPTGI VRQGKQVSYV RNSVKATVDA YDGTVTLFQF
     DRDDPVLRTW MRAFPGTVKS EDQIPDELRA HFRYPEDLFE VQRSLLAKYH VDEPREFFTT
     NAFWSVPSDP TNDANATQPP FYVLVGDQQS AQPSFRLASA MVGYNREFLS AYISAHSDPA
     NYGKLTVLEL PTDTLTQGPQ QIQNSMISDT RVASERTLLE RSNRIHYGNL LSLPIADGGV
     LYVEPLYTER ISTSPSSSTF PQLSRVLVSV REPRTEGGVR VGYAPTLAES LDQVFGPGTG
     RVATAPGGDA ASAPPPGAGG PAPPQAVPPP RTTQPPAAPP RGPDVPPATV AELRETLADL
     RAVLDRLEKA IDAAETPGG