ID   Y095_TREPA              Reviewed;         648 AA.
AC   O83133;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=TPR repeat-containing protein TP_0095;
GN   OrderedLocusNames=TP_0095;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
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DR   EMBL; AE000520; AAC65099.1; -; Genomic_DNA.
DR   PIR; C71366; C71366.
DR   RefSeq; WP_010881544.1; NC_021490.2.
DR   AlphaFoldDB; O83133; -.
DR   SMR; O83133; -.
DR   IntAct; O83133; 16.
DR   STRING; 243276.TPANIC_0095; -.
DR   EnsemblBacteria; AAC65099; AAC65099; TP_0095.
DR   GeneID; 57878635; -.
DR   KEGG; tpa:TP_0095; -.
DR   eggNOG; COG0457; Bacteria.
DR   HOGENOM; CLU_422062_0_0_12; -.
DR   OMA; YSERASC; -.
DR   OrthoDB; 215967at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   Gene3D; 1.25.40.10; -; 5.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   Pfam; PF13174; TPR_6; 2.
DR   Pfam; PF13176; TPR_7; 1.
DR   SMART; SM00028; TPR; 8.
DR   SUPFAM; SSF48452; SSF48452; 3.
DR   PROSITE; PS50005; TPR; 8.
DR   PROSITE; PS50293; TPR_REGION; 2.
PE   4: Predicted;
KW   Reference proteome; Repeat; TPR repeat.
FT   CHAIN           1..648
FT                   /note="TPR repeat-containing protein TP_0095"
FT                   /id="PRO_0000106452"
FT   REPEAT          1..30
FT                   /note="TPR 1"
FT   REPEAT          76..109
FT                   /note="TPR 2"
FT   REPEAT          110..143
FT                   /note="TPR 3"
FT   REPEAT          144..177
FT                   /note="TPR 4"
FT   REPEAT          219..252
FT                   /note="TPR 5"
FT   REPEAT          325..358
FT                   /note="TPR 6"
FT   REPEAT          428..461
FT                   /note="TPR 7"
FT   REPEAT          527..562
FT                   /note="TPR 8"
FT   REPEAT          597..630
FT                   /note="TPR 9"
SQ   SEQUENCE   648 AA;  72380 MW;  32A2A994F991FE69 CRC64;
     MTSTQARIRE AVRAGSVRDY ARAIRILEEL AASGKAEGCH HPDGGAVYER GAQEEWNEGS
     SESHAHGGDG TQDAYPEIYL YLARAYHAQR QYARAVAYAT VYSRRVPRDG AGWFFLGRSY
     LALHQGGYAV AALRRSVREN PASLGAQALL GLAYLRSKKP RAARMVFEQA LAQYPDNKRL
     NAGYLNSLFV EAVQHLKRGS ADLARQMFTF LINQDVDGVA PRLYLAHAFR SLKHFPEALT
     QYRAASAFAP HDPALKWYEA AMLVEMGCLS QAAALLSTLG VSIERDQISD RFLVMGAVRK
     HMEEGAWARA ASAAHLYLKT FGGSVEIHLL MAEVHRRAGR VNVALNHYTR AMKIEPKNCY
     PHYGLMVCLQ EARRWQELAK AIRRAEGAGC DAQDCYYYRV ITAAHLSNPP EEVLPHLQEL
     ARGGKADQLL FNALGVTYVR LGMADLALRW YEKTLLLDAE DEEACVGLIA CYEALCDDAR
     AYTQYGAYLS RWRDNRVIRK DFIAFLERTE RWSEAADHIE LLASGERGGF WGTRLAFARK
     KAGQYRQAAI IYRALLRQRP DERVLLHNLV YCLDKMGQAD AGLRLLRAAC NAFGTSVESR
     LIEGVLCLHT RRINAAIRTL RAVLEQQPGY TAASELLAKA YALASSRA