ID   Y097_MYCTO              Reviewed;         289 AA.
AC   P9WG82; L0T5I4; P67755; Q10893;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 42.
DE   RecName: Full=Putative dioxygenase MT0106;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=MT0106;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- COFACTOR:
CC       Name=Fe(2+); Xref=ChEBI:CHEBI:29033; Evidence={ECO:0000250};
CC       Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000250};
CC   -!- SIMILARITY: Belongs to the TfdA dioxygenase family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK44328.1; -; Genomic_DNA.
DR   PIR; A70751; A70751.
DR   RefSeq; WP_003400786.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WG82; -.
DR   SMR; P9WG82; -.
DR   EnsemblBacteria; AAK44328; AAK44328; MT0106.
DR   GeneID; 45424062; -.
DR   KEGG; mtc:MT0106; -.
DR   PATRIC; fig|83331.31.peg.111; -.
DR   HOGENOM; CLU_036005_2_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.130.10; -; 1.
DR   InterPro; IPR042098; TauD-like_sf.
DR   InterPro; IPR003819; TauD/TfdA-like.
DR   Pfam; PF02668; TauD; 1.
PE   3: Inferred from homology;
KW   Dioxygenase; Iron; Metal-binding; Oxidoreductase.
FT   CHAIN           1..289
FT                   /note="Putative dioxygenase MT0106"
FT                   /id="PRO_0000428407"
FT   BINDING         97
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250"
FT   BINDING         99
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250"
FT   BINDING         260
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   289 AA;  32641 MW;  FD38D0283E0E9F95 CRC64;
     MTLKVKGEGL GAQVTGVDPK NLDDITTDEI RDIVYTNKLV VLKDVHPSPR EFIKLGRIIG
     QIVPYYEPMY HHEDHPEIFV SSTEEGQGVP KTGAFWHIDY MFMPEPFAFS MVLPLAVPGH
     DRGTYFIDLA RVWQSLPAAK RDPARGTVST HDPRRHIKIR PSDVYRPIGE VWDEINRTTP
     PIKWPTVIRH PKTGQEILYI CATGTTKIED KDGNPVDPEV LQELMAATGQ LDPEYQSPFI
     HTQHYQVGDI ILWDNRVLMH RAKHGSAAGT LTTYRLTMLD GLKTPGYAA