ID   Y097_STAAR              Reviewed;         191 AA.
AC   Q6GKL1;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=HTH-type transcriptional regulator SAR0097;
GN   OrderedLocusNames=SAR0097;
OS   Staphylococcus aureus (strain MRSA252).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282458;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MRSA252;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
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DR   EMBL; BX571856; CAG39123.1; -; Genomic_DNA.
DR   RefSeq; WP_000414485.1; NC_002952.2.
DR   AlphaFoldDB; Q6GKL1; -.
DR   SMR; Q6GKL1; -.
DR   KEGG; sar:SAR0097; -.
DR   HOGENOM; CLU_069356_17_2_9; -.
DR   OMA; EHYERWH; -.
DR   OrthoDB; 2047542at2; -.
DR   Proteomes; UP000000596; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   Pfam; PF00440; TetR_N; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..191
FT                   /note="HTH-type transcriptional regulator SAR0097"
FT                   /id="PRO_0000286698"
FT   DOMAIN          12..74
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
FT   DNA_BIND        37..56
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
SQ   SEQUENCE   191 AA;  22399 MW;  CCD319D53C30101F CRC64;
     MEKNQRKKRS DAEYNQQIIL TTMEDLLEQG EDISTKKMSD IAKISGVGVG TLYRHFESKT
     LLCQAIMDKK VDQMFIEIED ILAENTQWPV RDKINVILTK YLDLKEANFT TLNFIEKSSS
     HSSSVINIPF FERLKNLLIQ QFENVHSIAD LDFKLNLMLN AFSSDFYYFV KHNQKLTKQQ
     FLDKLLDLYL K