Y1002_RHIME
ID Y1002_RHIME Reviewed; 525 AA.
AC Q52969;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2000, sequence version 2.
DT 25-MAY-2022, entry version 143.
DE RecName: Full=Uncharacterized sensor-like histidine kinase R01002;
DE EC=2.7.13.3;
GN OrderedLocusNames=R01002; ORFNames=SMc00059;
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-87.
RC STRAIN=RCR2011 / SU47;
RX PubMed=7756693; DOI=10.1094/mpmi-8-0267;
RA Keller M., Roxlau A., Weng W.M., Schmidt M., Quandt J., Niehaus K.,
RA Jording D., Arnold W., Puehler A.;
RT "Molecular analysis of the Rhizobium meliloti mucR gene regulating the
RT biosynthesis of the exopolysaccharides succinoglycan and galactoglucan.";
RL Mol. Plant Microbe Interact. 8:267-277(1995).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3;
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AL591688; CAC45574.1; -; Genomic_DNA.
DR EMBL; L37353; AAA74242.1; -; Genomic_DNA.
DR RefSeq; NP_385108.1; NC_003047.1.
DR RefSeq; WP_010968980.1; NC_003047.1.
DR AlphaFoldDB; Q52969; -.
DR SMR; Q52969; -.
DR STRING; 266834.SMc00059; -.
DR EnsemblBacteria; CAC45574; CAC45574; SMc00059.
DR GeneID; 61602466; -.
DR KEGG; sme:SMc00059; -.
DR PATRIC; fig|266834.11.peg.2403; -.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_000445_89_22_5; -.
DR OMA; FAYLRMD; -.
DR Proteomes; UP000001976; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 3.30.565.10; -; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF47384; SSF47384; 1.
DR SUPFAM; SSF55874; SSF55874; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell membrane; Kinase; Membrane; Nucleotide-binding;
KW Phosphoprotein; Reference proteome; Transferase; Transmembrane;
KW Transmembrane helix; Two-component regulatory system.
FT CHAIN 1..525
FT /note="Uncharacterized sensor-like histidine kinase R01002"
FT /id="PRO_0000074925"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 173..228
FT /note="PAC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00141"
FT DOMAIN 246..466
FT /note="Histidine kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00107"
FT REGION 506..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 249
FT /note="Phosphohistidine; by autocatalysis"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00107"
SQ SEQUENCE 525 AA; 55899 MW; 5366357A463F99F0 CRC64;
MAGRWTSLVD EAAAPWLPRG GLGSAIARHD FRRLRAVAAV SLTALPIVPL ALTLALPVSA
ALPAGAALWA SASLLAAAAA IAGGREFPTD GEVEFAPAPE LPDLNAAYDL FAGLVTVHDT
RGHVLSVHGR DASEYLKLMR DPHGRGFIEQ IHVSDRIAFL RAIDSLRLDS ERSAVDIRLE
RTSADGPQFA HIYCEMTPLR DAEGNLLAIV AQSRDVSEEA RLQAEAAAKA AHAESANDAK
TRFLAAVSHE LRTPLNAILG FSDVLAGEYF GKLENDRQRE YVSLIHQSGT HLLSVVNTML
DMSKIEAGRY ELLLEPFRVA EAIAACEAML SHQAREKGVR LTSRVTRSVG EINADQRAFQ
QILINLIGNA IKFTDRGGLV TVDAALEGNM LKLTVSDTGI GIAADKLQML GQPFVQIQND
YTRRYEGTGL GLSLVKGLAE LHGGDVSIRS AEGEGTVIVV TIPSDASGAA ERQCADAPVT
VEFPPRLKQH ADGKREAGVP ALSEALHTGE IGREGGHGAA QAKTA
