ID   Y1003_TREPA             Reviewed;         345 AA.
AC   O83968;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Uncharacterized protein TP_1003;
GN   OrderedLocusNames=TP_1003;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65959.1; -; Genomic_DNA.
DR   PIR; E71254; E71254.
DR   RefSeq; WP_010882447.1; NC_021490.2.
DR   AlphaFoldDB; O83968; -.
DR   IntAct; O83968; 1.
DR   STRING; 243276.TPANIC_1003; -.
DR   EnsemblBacteria; AAC65959; AAC65959; TP_1003.
DR   GeneID; 57879514; -.
DR   KEGG; tpa:TP_1003; -.
DR   HOGENOM; CLU_803954_0_0_12; -.
DR   OMA; NIYLLWT; -.
DR   OrthoDB; 1411290at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..345
FT                   /note="Uncharacterized protein TP_1003"
FT                   /id="PRO_0000202372"
FT   TRANSMEM        9..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        84..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        116..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        182..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        269..286
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        291..308
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        313..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   345 AA;  37828 MW;  8745F06B874BA070 CRC64;
     MTIAGRNKVV AFSIVLSALL CSISLLQAAF VLSGGSLPQL AVARVPPLLH TTGRAFMHVL
     TFLLPEAAAR SLAAVSTAPS NSSTLVAILG TGLSAPLLLT YLLRRFEKTH AVEISYFSLF
     LCALNFEGVR LFLPILYTGT LTTYAGNVPM QIVMFFRSLA LLALFASGIF AKKTLTRQEG
     AVVFVLCTVA FLISRYTTIH TIHAYRPSQS TQGAILLAQP ISESGSIIDS TGEEKTLKVR
     SSAHRKTRIL VTPQRNFTFY YGSHAWHRWF FWTTAVLSAL SYGVLGHTLQ ISHYYIAAAA
     LPFVIAGYRL LTHGLTWSAC IVGLFLLNTA SVFFIRSVHR VHIWQ