ID   Y1005_METKA             Reviewed;         325 AA.
AC   Q8TWM7;
DT   25-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Putative HTH-type transcriptional regulatory protein MK1005 {ECO:0000255|HAMAP-Rule:MF_00584};
GN   OrderedLocusNames=MK1005;
OS   Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938).
OC   Archaea; Euryarchaeota; Methanopyri; Methanopyrales; Methanopyraceae;
OC   Methanopyrus.
OX   NCBI_TaxID=190192;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AV19 / DSM 6324 / JCM 9639 / NBRC 100938;
RX   PubMed=11930014; DOI=10.1073/pnas.032671499;
RA   Slesarev A.I., Mezhevaya K.V., Makarova K.S., Polushin N.N.,
RA   Shcherbinina O.V., Shakhova V.V., Belova G.I., Aravind L., Natale D.A.,
RA   Rogozin I.B., Tatusov R.L., Wolf Y.I., Stetter K.O., Malykh A.G.,
RA   Koonin E.V., Kozyavkin S.A.;
RT   "The complete genome of hyperthermophile Methanopyrus kandleri AV19 and
RT   monophyly of archaeal methanogens.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:4644-4649(2002).
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DR   EMBL; AE009439; AAM02218.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8TWM7; -.
DR   SMR; Q8TWM7; -.
DR   STRING; 190192.MK1005; -.
DR   PRIDE; Q8TWM7; -.
DR   EnsemblBacteria; AAM02218; AAM02218; MK1005.
DR   KEGG; mka:MK1005; -.
DR   HOGENOM; CLU_075726_0_0_2; -.
DR   Proteomes; UP000001826; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00584; HTH_type_cro_C1; 1.
DR   InterPro; IPR020886; Arc_TR_HTH.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..325
FT                   /note="Putative HTH-type transcriptional regulatory protein
FT                   MK1005"
FT                   /id="PRO_0000144857"
FT   DOMAIN          128..190
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
FT   DNA_BIND        139..158
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
SQ   SEQUENCE   325 AA;  36979 MW;  31D97A4FAE9D8BD7 CRC64;
     MRAELCADLE EALRAGGHEV VRIERACFDI FVRTRDGRAY IVKVLINADG LRREVAEELR
     RISHFLEAVP VVVALKRHTG PLEKGVVYHR YEVPVLDPLT FARLVEGEPP KAVADRGGQY
     VVIRADEVDE LDVSRVRRRQ LRREGGRITL ARAEEADVEG VPVELKTPEH VDTGRDRMTR
     FERRVAELLE RMGAERTGKV RRAPFKLLAK DGETVLARAE EGGDRESIAL RDVASATGSM
     GVIVTRERCK DTYVPTIDIG TLEEIKDLED LKEYLQERDP EERVRRLVEE AGITSPREIA
     QRTGIRESVI REFLRRMGIT DERKV