CAPP_PHOLL
ID CAPP_PHOLL Reviewed; 878 AA.
AC Q7MAX5;
DT 24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-2003, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000255|HAMAP-Rule:MF_00595};
DE Short=PEPC {ECO:0000255|HAMAP-Rule:MF_00595};
DE Short=PEPCase {ECO:0000255|HAMAP-Rule:MF_00595};
DE EC=4.1.1.31 {ECO:0000255|HAMAP-Rule:MF_00595};
GN Name=ppc {ECO:0000255|HAMAP-Rule:MF_00595}; OrderedLocusNames=plu4746;
OS Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 /
OS TT01).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Photorhabdus.
OX NCBI_TaxID=243265;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15139 / CIP 105565 / TT01;
RX PubMed=14528314; DOI=10.1038/nbt886;
RA Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A.,
RA Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F.,
RA Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C.,
RA Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M.,
RA Glaser P., Boemare N., Danchin A., Kunst F.;
RT "The genome sequence of the entomopathogenic bacterium Photorhabdus
RT luminescens.";
RL Nat. Biotechnol. 21:1307-1313(2003).
CC -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC for the tricarboxylic acid cycle. {ECO:0000255|HAMAP-Rule:MF_00595}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00595};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00595};
CC -!- SIMILARITY: Belongs to the PEPCase type 1 family. {ECO:0000255|HAMAP-
CC Rule:MF_00595}.
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DR EMBL; BX571874; CAE17118.1; -; Genomic_DNA.
DR RefSeq; WP_011148814.1; NC_005126.1.
DR AlphaFoldDB; Q7MAX5; -.
DR SMR; Q7MAX5; -.
DR STRING; 243265.plu4746; -.
DR EnsemblBacteria; CAE17118; CAE17118; plu4746.
DR GeneID; 24168737; -.
DR KEGG; plu:plu4746; -.
DR eggNOG; COG2352; Bacteria.
DR HOGENOM; CLU_006557_2_0_6; -.
DR OMA; PWVFGWT; -.
DR OrthoDB; 398146at2; -.
DR BioCyc; PLUM243265:PLU_RS23550-MON; -.
DR Proteomes; UP000002514; Chromosome.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR HAMAP; MF_00595; PEPcase_type1; 1.
DR InterPro; IPR021135; PEP_COase.
DR InterPro; IPR022805; PEP_COase_bac/pln-type.
DR InterPro; IPR018129; PEP_COase_Lys_AS.
DR InterPro; IPR033129; PEPCASE_His_AS.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR PANTHER; PTHR30523; PTHR30523; 1.
DR Pfam; PF00311; PEPcase; 1.
DR PRINTS; PR00150; PEPCARBXLASE.
DR SUPFAM; SSF51621; SSF51621; 1.
DR PROSITE; PS00781; PEPCASE_1; 1.
DR PROSITE; PS00393; PEPCASE_2; 1.
PE 3: Inferred from homology;
KW Carbon dioxide fixation; Lyase; Magnesium; Reference proteome.
FT CHAIN 1..878
FT /note="Phosphoenolpyruvate carboxylase"
FT /id="PRO_0000166608"
FT ACT_SITE 137
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00595"
FT ACT_SITE 545
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00595"
SQ SEQUENCE 878 AA; 98823 MW; A943F294497764EE CRC64;
MNQQYSAMRS NVSMLGKLLG DTIKEALGED ILDKVETIRK LSKSSRAGNE AHRQQLLSTL
QNLSNNELLP VARAFNQFLN LTNVAEQYHS ISPHGEAASN PVALAKLFTR LKEKNFNNGD
LKKAVNELSI ELVLTAHPTE IARRTLIHKL VAVNTCLSQL DHDDLADYER NNIMRRLRQL
VAQSWHTDEI RKIRPTPIDE AKWGFAMVEN SLWEGVPAFL REFNEQLEES IDYSLPVEAV
PVRFTSWMGG DRDGNPNVTA EVTRHVLLLS RWKAADLFLK DIQVLVSELS MSECTPEVRK
LAGGDEILEP YREIAKKLRT QLSNTLTYLE KQLKGEQVLP PTDLLVDNEQ LWQPLYACYQ
SLKTCGMEII ANGQLLDILR RIRCFGLSLV RIDVRQESTR HTTAISELTQ YLELGDYASW
SEEEKQAFLL YELHSKRPLI PHNWQPSAET QEVFATCKVI AESPQDAIAA YVISMAKAPS
DVLAVHLLLK EAGCPFTLPV APLFETLDDL NNAENIIQQL MNIQWYRELI HDKQMVMIGY
SDSAKDAGVM AAAWAQYRAQ DALINVCEKE GITLTLFHGR GGTIGRGGAP AHAALLSQPP
GSLKGGLRVT EQGEMIRFKF GLPQVTISSL ALYASAILEA NLLPPPEPKP EWHQVMDTLS
DVSCKMYRDY VREQPDFVPY FRAATPEQEL AKLPLGSRPA KRHPAGGVES LRAIPWIFAW
TQNRLMLPAW LGAGAALQQV VNDGKQDVLA EMCRDWPFFT TRIGMLEMVF AKADLWLAEY
YDHRLVDKNL WPLGQKLRKQ LSADIKTVLA ISKDEHLMAD LPWIAESIAL RNVYTDPLNV
LQVELLLRSR QQQYSDPQVE QALMVTIAGI AAGMRNTG