ID   CAPP_PHOPR              Reviewed;         876 AA.
AC   Q6LVH1;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   30-AUG-2005, sequence version 2.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000255|HAMAP-Rule:MF_00595};
DE            Short=PEPC {ECO:0000255|HAMAP-Rule:MF_00595};
DE            Short=PEPCase {ECO:0000255|HAMAP-Rule:MF_00595};
DE            EC=4.1.1.31 {ECO:0000255|HAMAP-Rule:MF_00595};
GN   Name=ppc {ECO:0000255|HAMAP-Rule:MF_00595}; OrderedLocusNames=PBPRA0265;
OS   Photobacterium profundum (strain SS9).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Photobacterium.
OX   NCBI_TaxID=298386;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1253 / SS9;
RX   PubMed=15746425; DOI=10.1126/science.1103341;
RA   Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M.,
RA   Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C.,
RA   Bartlett D.H., Valle G.;
RT   "Life at depth: Photobacterium profundum genome sequence and expression
RT   analysis.";
RL   Science 307:1459-1461(2005).
CC   -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC       for the tricarboxylic acid cycle. {ECO:0000255|HAMAP-Rule:MF_00595}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC         phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00595};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00595};
CC   -!- SIMILARITY: Belongs to the PEPCase type 1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00595}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAG18704.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CR378663; CAG18704.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_011217078.1; NC_006370.1.
DR   AlphaFoldDB; Q6LVH1; -.
DR   SMR; Q6LVH1; -.
DR   STRING; 298386.PBPRA0265; -.
DR   EnsemblBacteria; CAG18704; CAG18704; PBPRA0265.
DR   KEGG; ppr:PBPRA0265; -.
DR   eggNOG; COG2352; Bacteria.
DR   HOGENOM; CLU_006557_2_0_6; -.
DR   OrthoDB; 398146at2; -.
DR   Proteomes; UP000000593; Chromosome 1.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   PANTHER; PTHR30523; PTHR30523; 1.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; SSF51621; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation; Lyase; Magnesium; Reference proteome.
FT   CHAIN           1..876
FT                   /note="Phosphoenolpyruvate carboxylase"
FT                   /id="PRO_0000166609"
FT   ACT_SITE        138
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00595"
FT   ACT_SITE        543
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00595"
SQ   SEQUENCE   876 AA;  98542 MW;  E6BFC1FF0E82FBF8 CRC64;
     MNEKYSALRS NVSMLGHMLG NTIKDAHGEP LFDKVETIRK LSKSARAGND SDRAKLIDEL
     QNLPDDQLLP VARAFSQFLN LTNIAEQYHT ISRHCEEQIC SPDSIDSLFG KLNANSISQL
     DSIQAVRDLN IELVLTAHPT EIARRTMIHK LVQINKCLSN LELSELSHSE RQRVEQRLEQ
     LIAQAWHSDV IRKQRPTPLD EAKWGFAVVE NSLWHAVPEF LRQFDEKLMR HLGEKLPLDA
     SPVKFTSWMG GDRDGNPFVT SEVTREVMLL SRWKAADLFL GDIQELVSEL SMVKCNDQVR
     ELAGEEHEPY RAILKDLRTK LTNTRDVLAA KINKQDAPNL ATIDDVDQLW TPLHACYQSL
     RECGMGIIAD GLLLDVLRRI KCFGIHLVRL DIRQESTRHS DVISELTRYL GLGDYEQWNE
     QDKVAFLVRE LASKRPLLPL AWQPSAEVQE VLDTCKAVAE QSREALGAYV ISMARTASDV
     LAVHLLLKEA GCPFRLDVCP LFETLDDLNN GASVIKELMS IDWYRGFIQN HQMVMIGYSD
     SAKDAGVMAA GWAQYRAMEE LVEVCEDASV ELTLFHGRGG SIGRGGAPAH AALLSQPPRS
     LKGGLRVTEQ GEMIRFKLGL PDVAVNSLSL YASATLEANL LPPPAPKKEW CDLMDVLSEV
     SCESYRNVVR GSEEFVPYFR AATPELELGK LPLGSRPAKR NPNGGVESLR AIPWIFAWSQ
     NRLLLPAWLG AGEAIQYSID KGHAQLLEDM CREWPFFSTR LGMLEMVYTK TNVGIAEYYD
     QRLTDKSLWP LGQKLRDQLQ QDIKAVLNVE NNAHLMEQNP WGAEAIRLRN IYVEPLNMLQ
     AELLYRTRQQ DEPSPILEEA LMVSIAGIAT GMRNTG