ID   Y1009_STAA1             Reviewed;         169 AA.
AC   A7X0P2;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Putative phosphoesterase SAHV_1009 {ECO:0000255|HAMAP-Rule:MF_01444};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_01444};
GN   OrderedLocusNames=SAHV_1009;
OS   Staphylococcus aureus (strain Mu3 / ATCC 700698).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=418127;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mu3 / ATCC 700698;
RX   PubMed=17954695; DOI=10.1128/aac.00534-07;
RA   Neoh H.-M., Cui L., Yuzawa H., Takeuchi F., Matsuo M., Hiramatsu K.;
RT   "Mutated response regulator graR is responsible for phenotypic conversion
RT   of Staphylococcus aureus from heterogeneous vancomycin-intermediate
RT   resistance to vancomycin-intermediate resistance.";
RL   Antimicrob. Agents Chemother. 52:45-53(2008).
CC   -!- SIMILARITY: Belongs to the 2H phosphoesterase superfamily. YjcG family.
CC       {ECO:0000255|HAMAP-Rule:MF_01444}.
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DR   EMBL; AP009324; BAF77892.1; -; Genomic_DNA.
DR   RefSeq; WP_000600387.1; NC_009782.1.
DR   AlphaFoldDB; A7X0P2; -.
DR   SMR; A7X0P2; -.
DR   GeneID; 66839208; -.
DR   KEGG; saw:SAHV_1009; -.
DR   HOGENOM; CLU_132020_0_0_9; -.
DR   OMA; RELQFPY; -.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01444; 2H_phosphoesterase_YjcG; 1.
DR   InterPro; IPR009097; Cyclic_Pdiesterase.
DR   InterPro; IPR022932; YjcG.
DR   SUPFAM; SSF55144; SSF55144; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..169
FT                   /note="Putative phosphoesterase SAHV_1009"
FT                   /id="PRO_1000068568"
FT   MOTIF           34..37
FT                   /note="HXTX 1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01444"
FT   MOTIF           115..118
FT                   /note="HXTX 2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01444"
FT   ACT_SITE        34
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01444"
FT   ACT_SITE        115
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01444"
SQ   SEQUENCE   169 AA;  19327 MW;  AF0C2B37F83AC5D2 CRC64;
     MILGLALIPS KSFQEAVDSY RKRYDKQYSR IKPHVTIKAP FEIEDGDLDS VIEQVRARIN
     GIPAVEVHAT KASSFKPTNN VIYFKVAKTD DLEELFNRFN GEDFYGEAEH VFVPHFTIAQ
     GLSSQEFEDI FGQVALAGVD HKEIIDELTL LRFDDDEDKW KVIETFKLA