Y1009_YERPE
ID Y1009_YERPE Reviewed; 410 AA.
AC Q8ZH96; Q0WI34;
DT 02-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=Peptidase T-like protein YPO1009/y3403/YP_3421;
DE EC=3.4.11.-;
GN OrderedLocusNames=YPO1009, y3403, YP_3421;
OS Yersinia pestis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM10+ / Biovar Mediaevalis;
RX PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT "Genome sequence of Yersinia pestis KIM.";
RL J. Bacteriol. 184:4601-4611(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250};
CC Note=Binds 2 Zn(2+) ions per subunit. {ECO:0000250};
CC -!- SIMILARITY: Belongs to the peptidase M20B family. {ECO:0000305}.
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DR EMBL; AL590842; CAL19675.1; -; Genomic_DNA.
DR EMBL; AE009952; AAM86953.1; -; Genomic_DNA.
DR EMBL; AE017042; AAS63582.1; -; Genomic_DNA.
DR PIR; AI0123; AI0123.
DR RefSeq; WP_002211633.1; NZ_WUCM01000051.1.
DR RefSeq; YP_002346054.1; NC_003143.1.
DR AlphaFoldDB; Q8ZH96; -.
DR SMR; Q8ZH96; -.
DR IntAct; Q8ZH96; 2.
DR STRING; 214092.YPO1009; -.
DR PaxDb; Q8ZH96; -.
DR DNASU; 1148350; -.
DR EnsemblBacteria; AAM86953; AAM86953; y3403.
DR EnsemblBacteria; AAS63582; AAS63582; YP_3421.
DR GeneID; 57977552; -.
DR KEGG; ype:YPO1009; -.
DR KEGG; ypk:y3403; -.
DR KEGG; ypm:YP_3421; -.
DR PATRIC; fig|214092.21.peg.1297; -.
DR eggNOG; COG2195; Bacteria.
DR HOGENOM; CLU_053676_0_0_6; -.
DR OMA; WTIDCCE; -.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000001019; Chromosome.
DR Proteomes; UP000002490; Chromosome.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0045148; F:tripeptide aminopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006518; P:peptide metabolic process; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR InterPro; IPR001261; ArgE/DapE_CS.
DR InterPro; IPR036264; Bact_exopeptidase_dim_dom.
DR InterPro; IPR002933; Peptidase_M20.
DR InterPro; IPR011650; Peptidase_M20_dimer.
DR InterPro; IPR010161; Peptidase_M20B.
DR PANTHER; PTHR42994:SF1; PTHR42994:SF1; 1.
DR Pfam; PF07687; M20_dimer; 1.
DR Pfam; PF01546; Peptidase_M20; 1.
DR PIRSF; PIRSF037215; Peptidase_M20B; 1.
DR SUPFAM; SSF55031; SSF55031; 1.
DR TIGRFAMs; TIGR01882; peptidase-T; 1.
DR PROSITE; PS00759; ARGE_DAPE_CPG2_2; 1.
PE 3: Inferred from homology;
KW Hydrolase; Metal-binding; Metalloprotease; Protease; Reference proteome;
KW Zinc.
FT CHAIN 1..410
FT /note="Peptidase T-like protein YPO1009/y3403/YP_3421"
FT /id="PRO_0000185337"
FT ACT_SITE 84
FT /evidence="ECO:0000250"
FT ACT_SITE 176
FT /note="Proton acceptor"
FT /evidence="ECO:0000250"
FT BINDING 82
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 144
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 144
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 177
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 200
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 382
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
SQ SEQUENCE 410 AA; 44891 MW; F80AAD13399E6045 CRC64;
MTIALSEQLT NRFFRYLAVS SQSDAASPTL PSTEGQHKMA QMLAEELRQL GLEDILIDEH
ATVTARKPGN QPTAPRIGFI THIDTVDVGL SPDIHPQRLR FTGSDLCLNA EQGIYLRTAE
HPEILRYQGE EIIFSDGTSV LGADNKAAVT VVMTLLENLT ADDCHGDIVV AFVPDEEIGL
RGAKALDLAR FDVDFAYTID CCELGEVVYE NFNAASAEID IIGVTAHPMS AKNVLINPIR
VAYDIISEFS PQETPEHTEG REGYVWFTDM TANPNSAKLK IAIRDFDNVS FAARKAYIGE
VVAKVSAQYP RAKISYSVTD VYSNISNSIG EDKRAIDLIF SSMAELNIEP KVIPMRGGTD
GAALSTQGLL TPNYFTGAHN FHSPFEFLPI SSFVKSYQLT RTICLSAAKA
