ID   Y100_MYCBO              Reviewed;         289 AA.
AC   P67756; A0A1R3XUA9; Q10893; X2BE10;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Putative dioxygenase Mb0100;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=BQ2027_MB0100;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- COFACTOR:
CC       Name=Fe(2+); Xref=ChEBI:CHEBI:29033; Evidence={ECO:0000250};
CC       Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000250};
CC   -!- SIMILARITY: Belongs to the TfdA dioxygenase family. {ECO:0000305}.
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DR   EMBL; LT708304; SIT98503.1; -; Genomic_DNA.
DR   RefSeq; NP_853768.1; NC_002945.3.
DR   RefSeq; WP_003400786.1; NC_002945.4.
DR   AlphaFoldDB; P67756; -.
DR   SMR; P67756; -.
DR   GeneID; 45424062; -.
DR   PATRIC; fig|233413.5.peg.112; -.
DR   OMA; VWDNRSL; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.130.10; -; 1.
DR   InterPro; IPR042098; TauD-like_sf.
DR   InterPro; IPR003819; TauD/TfdA-like.
DR   Pfam; PF02668; TauD; 1.
PE   3: Inferred from homology;
KW   Dioxygenase; Iron; Metal-binding; Oxidoreductase.
FT   CHAIN           1..289
FT                   /note="Putative dioxygenase Mb0100"
FT                   /id="PRO_0000194019"
FT   BINDING         97
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250"
FT   BINDING         99
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250"
FT   BINDING         260
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   289 AA;  32641 MW;  FD38D0283E0E9F95 CRC64;
     MTLKVKGEGL GAQVTGVDPK NLDDITTDEI RDIVYTNKLV VLKDVHPSPR EFIKLGRIIG
     QIVPYYEPMY HHEDHPEIFV SSTEEGQGVP KTGAFWHIDY MFMPEPFAFS MVLPLAVPGH
     DRGTYFIDLA RVWQSLPAAK RDPARGTVST HDPRRHIKIR PSDVYRPIGE VWDEINRTTP
     PIKWPTVIRH PKTGQEILYI CATGTTKIED KDGNPVDPEV LQELMAATGQ LDPEYQSPFI
     HTQHYQVGDI ILWDNRVLMH RAKHGSAAGT LTTYRLTMLD GLKTPGYAA