ID   Y1014_TREPA             Reviewed;         644 AA.
AC   O83978;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Uncharacterized protein TP_1014;
GN   OrderedLocusNames=TP_1014;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65972.1; -; Genomic_DNA.
DR   PIR; B71253; B71253.
DR   RefSeq; WP_010882458.1; NC_021490.2.
DR   AlphaFoldDB; O83978; -.
DR   STRING; 243276.TPANIC_1014; -.
DR   EnsemblBacteria; AAC65972; AAC65972; TP_1014.
DR   GeneID; 57879525; -.
DR   KEGG; tpa:TP_1014; -.
DR   eggNOG; ENOG5031C4W; Bacteria.
DR   HOGENOM; CLU_492532_0_0_12; -.
DR   OMA; GKESIIR; -.
DR   OrthoDB; 201840at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
PE   4: Predicted;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..644
FT                   /note="Uncharacterized protein TP_1014"
FT                   /id="PRO_0000202373"
FT   TRANSMEM        16..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          586..613
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        586..610
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   644 AA;  71127 MW;  564A8BE8307DBD1F CRC64;
     MVCSITLLKV RSKRHLLSYL GVVGVGIAGL CIYRSVWGSR PFLERLARAD SLIAQERKGA
     ALRGLARMVG HARESSQYLS IAKRQMELSA SAAALRTLQR GIRRSADDGR LAALVIHLLL
     REARFEEAIS YVPRVVHKGY ESIGAEALIK AALIGSRTGG DSPSRGSFHS ERAEHVPEEP
     VEFSQVQGGR DQAHVTAFPL DRGEEQFRVE PSPPIRHTTG IALARIAPAL WLAAFGVTGM
     HAFLQNAACA YARVGELHAA FRLYSRILGT EAPENTAFWA TVAYDAGQFS LVFELLPISL
     ARADLFGTYS AASTHARTHL LLAADAAFDG GDRARARAFW YAYVDRFPGT STHALYNLAL
     TAPHAQERVR MLAQCVEGDK TYYPAVACYA RESIAFRAAH RQRDSVTELL SERGVYSVQM
     EQEHFLSPHF PVEARSLLAE LAQEAMHGRA DVRFALEYFR FCYPAQKRLQ GSRGALWQLL
     EVFPVDTQVR RYARWFFFRI GEYESAFGLS DAGGGPEDAF YRALAAASRT GRVESILGGL
     VEATRAVEAR SAAFANIAIV LERMGKKTAA AEHFVLAADE ATRESVRQLQ KEAGEGEAEE
     HPRARPAAGK AQRWREWYQR AGQLLQQQGK TVAARALLQR AQAR