Y1017_HAEIN
ID Y1017_HAEIN Reviewed; 213 AA.
AC O86231;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Uncharacterized aquaporin-like protein HI_1017;
GN OrderedLocusNames=HI_1017;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
RN [2]
RP IDENTIFICATION.
RA White O., Clayton R.A., Kerlavage A.R., Fleischmann R.D., Peterson J.,
RA Hickey E., Dodson R., Gwinn M.;
RL Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- DOMAIN: Aquaporins contain two tandem repeats each containing three
CC membrane-spanning domains and a pore-forming loop with the signature
CC motif Asn-Pro-Ala (NPA).
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC {ECO:0000305}.
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DR EMBL; L42023; AAC22677.1; -; Genomic_DNA.
DR AlphaFoldDB; O86231; -.
DR SMR; O86231; -.
DR STRING; 71421.HI_1017; -.
DR EnsemblBacteria; AAC22677; AAC22677; HI_1017.
DR KEGG; hin:HI_1017; -.
DR eggNOG; COG0580; Bacteria.
DR HOGENOM; CLU_020019_9_2_6; -.
DR OMA; TIDFWEV; -.
DR PhylomeDB; O86231; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015254; F:glycerol channel activity; IBA:GO_Central.
DR GO; GO:0015793; P:glycerol transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.20.1080.10; -; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR000425; MIP.
DR Pfam; PF00230; MIP; 1.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; SSF81338; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..213
FT /note="Uncharacterized aquaporin-like protein HI_1017"
FT /id="PRO_0000064096"
FT TRANSMEM 22..42
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 63..83
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 112..132
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 188..208
FT /note="Helical"
FT /evidence="ECO:0000255"
FT MOTIF 43..45
FT /note="NPA 1"
FT MOTIF 164..166
FT /note="NPA 2"
SQ SEQUENCE 213 AA; 24053 MW; 2F80EFE512638963 CRC64;
MCQYFLKKIR NVWERWFTYR LWFGLSMVSI AVIFGPLTGA HVNPAVTIDF WEVGKFPTEL
VLVYIIAQCI GAFIVALIVW LLFKDHLDEE DNQNCQLGSF ATIATNSNNL RNLLSEIVTT
FSLLFILFTL NHQQPTNGVA MFFVFTGVAG GVMSFGGLTS YAINPARDFM LRLIHAIMPI
KNKGTSNFDY AWVPVLRPVI GAILAAWLYK ALF
