Y1019_STRR6
ID Y1019_STRR6 Reviewed; 279 AA.
AC Q8DPT4;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=DegV domain-containing protein spr1019;
GN OrderedLocusNames=spr1019;
OS Streptococcus pneumoniae (strain ATCC BAA-255 / R6).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=171101;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-255 / R6;
RX PubMed=11544234; DOI=10.1128/jb.183.19.5709-5717.2001;
RA Hoskins J., Alborn W.E. Jr., Arnold J., Blaszczak L.C., Burgett S.,
RA DeHoff B.S., Estrem S.T., Fritz L., Fu D.-J., Fuller W., Geringer C.,
RA Gilmour R., Glass J.S., Khoja H., Kraft A.R., Lagace R.E., LeBlanc D.J.,
RA Lee L.N., Lefkowitz E.J., Lu J., Matsushima P., McAhren S.M., McHenney M.,
RA McLeaster K., Mundy C.W., Nicas T.I., Norris F.H., O'Gara M., Peery R.B.,
RA Robertson G.T., Rockey P., Sun P.-M., Winkler M.E., Yang Y.,
RA Young-Bellido M., Zhao G., Zook C.A., Baltz R.H., Jaskunas S.R.,
RA Rosteck P.R. Jr., Skatrud P.L., Glass J.I.;
RT "Genome of the bacterium Streptococcus pneumoniae strain R6.";
RL J. Bacteriol. 183:5709-5717(2001).
CC -!- FUNCTION: May bind long-chain fatty acids, such as palmitate, and may
CC play a role in lipid transport or fatty acid metabolism. {ECO:0000250}.
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DR EMBL; AE007317; AAK99823.1; -; Genomic_DNA.
DR PIR; C97999; C97999.
DR RefSeq; NP_358613.1; NC_003098.1.
DR RefSeq; WP_000161389.1; NC_003098.1.
DR PDB; 6NR1; X-ray; 2.10 A; A/B=1-279.
DR PDBsum; 6NR1; -.
DR AlphaFoldDB; Q8DPT4; -.
DR SMR; Q8DPT4; -.
DR STRING; 171101.spr1019; -.
DR EnsemblBacteria; AAK99823; AAK99823; spr1019.
DR GeneID; 60233939; -.
DR KEGG; spr:spr1019; -.
DR PATRIC; fig|171101.6.peg.1109; -.
DR eggNOG; COG1307; Bacteria.
DR HOGENOM; CLU_048251_3_2_9; -.
DR OMA; EIHAKIN; -.
DR Proteomes; UP000000586; Chromosome.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1180.10; -; 1.
DR InterPro; IPR003797; DegV.
DR InterPro; IPR043168; DegV_C.
DR Pfam; PF02645; DegV; 1.
DR TIGRFAMs; TIGR00762; DegV; 1.
DR PROSITE; PS51482; DEGV; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Lipid-binding; Reference proteome.
FT CHAIN 1..279
FT /note="DegV domain-containing protein spr1019"
FT /id="PRO_0000209798"
FT DOMAIN 4..277
FT /note="DegV"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00815"
FT BINDING 62
FT /ligand="hexadecanoate"
FT /ligand_id="ChEBI:CHEBI:7896"
FT /evidence="ECO:0000250|UniProtKB:Q9X1H9"
FT BINDING 94
FT /ligand="hexadecanoate"
FT /ligand_id="ChEBI:CHEBI:7896"
FT /evidence="ECO:0000250|UniProtKB:Q9X1H9"
FT STRAND 5..9
FT /evidence="ECO:0007829|PDB:6NR1"
FT HELIX 16..22
FT /evidence="ECO:0007829|PDB:6NR1"
FT STRAND 25..27
FT /evidence="ECO:0007829|PDB:6NR1"
FT STRAND 30..33
FT /evidence="ECO:0007829|PDB:6NR1"
FT STRAND 36..39
FT /evidence="ECO:0007829|PDB:6NR1"
FT HELIX 40..42
FT /evidence="ECO:0007829|PDB:6NR1"
FT HELIX 48..55
FT /evidence="ECO:0007829|PDB:6NR1"
FT STRAND 61..63
FT /evidence="ECO:0007829|PDB:6NR1"
FT HELIX 67..77
FT /evidence="ECO:0007829|PDB:6NR1"
FT HELIX 78..80
FT /evidence="ECO:0007829|PDB:6NR1"
FT STRAND 84..88
FT /evidence="ECO:0007829|PDB:6NR1"
FT TURN 91..93
FT /evidence="ECO:0007829|PDB:6NR1"
FT HELIX 96..106
FT /evidence="ECO:0007829|PDB:6NR1"
FT STRAND 107..109
FT /evidence="ECO:0007829|PDB:6NR1"
FT STRAND 111..115
FT /evidence="ECO:0007829|PDB:6NR1"
FT HELIX 120..135
FT /evidence="ECO:0007829|PDB:6NR1"
FT HELIX 140..152
FT /evidence="ECO:0007829|PDB:6NR1"
FT STRAND 154..161
FT /evidence="ECO:0007829|PDB:6NR1"
FT HELIX 164..169
FT /evidence="ECO:0007829|PDB:6NR1"
FT HELIX 171..174
FT /evidence="ECO:0007829|PDB:6NR1"
FT STRAND 183..192
FT /evidence="ECO:0007829|PDB:6NR1"
FT STRAND 195..204
FT /evidence="ECO:0007829|PDB:6NR1"
FT HELIX 207..218
FT /evidence="ECO:0007829|PDB:6NR1"
FT TURN 219..221
FT /evidence="ECO:0007829|PDB:6NR1"
FT STRAND 224..233
FT /evidence="ECO:0007829|PDB:6NR1"
FT HELIX 236..245
FT /evidence="ECO:0007829|PDB:6NR1"
FT HELIX 246..248
FT /evidence="ECO:0007829|PDB:6NR1"
FT STRAND 254..257
FT /evidence="ECO:0007829|PDB:6NR1"
FT HELIX 260..266
FT /evidence="ECO:0007829|PDB:6NR1"
FT STRAND 271..277
FT /evidence="ECO:0007829|PDB:6NR1"
SQ SEQUENCE 279 AA; 30668 MW; E013F05826E545E8 CRC64;
MTKIKIVTDS SVTIEPELVK QLDITIVPLS VMIDNVVYSD ADLKEEGKFL QLMQESKNLP
KTSQPPVGVF AEIFEDLCKD GGQILAIHMS HALSGTVEAA RQGASLSTAD VIVVDSSFTD
QALKFQVVEA AKLAQEGKDM EAILSHVEEV KNHTELYIGV STLENLVKGG RIGRVTGLLS
SLLNIRVVMQ MKDHELQPMV KGRGTKTFKK WLDELITSLS ERAVAEIGIS YSGSDDWAKE
MKESLQAYVE KPISVLETGS IIQTHTGENA WAILIRYHS
