ID   Y101_STAAM              Reviewed;         745 AA.
AC   Q99XB1;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 121.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator SAV0101;
GN   OrderedLocusNames=SAV0101;
OS   Staphylococcus aureus (strain Mu50 / ATCC 700699).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158878;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mu50 / ATCC 700699;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
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DR   EMBL; BA000017; BAB56263.1; -; Genomic_DNA.
DR   RefSeq; WP_001188472.1; NC_002758.2.
DR   AlphaFoldDB; Q99XB1; -.
DR   SMR; Q99XB1; -.
DR   PaxDb; Q99XB1; -.
DR   EnsemblBacteria; BAB56263; BAB56263; SAV0101.
DR   KEGG; sav:SAV0101; -.
DR   HOGENOM; CLU_017624_1_0_9; -.
DR   OMA; TNGRFFR; -.
DR   PhylomeDB; Q99XB1; -.
DR   Proteomes; UP000002481; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR037923; HTH-like.
DR   InterPro; IPR018060; HTH_AraC.
DR   InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR   Pfam; PF12833; HTH_18; 1.
DR   PRINTS; PR00032; HTHARAC.
DR   SMART; SM00342; HTH_ARAC; 1.
DR   SUPFAM; SSF46689; SSF46689; 2.
DR   SUPFAM; SSF51215; SSF51215; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE   4: Predicted;
KW   DNA-binding; Repeat; Transcription; Transcription regulation.
FT   CHAIN           1..745
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   SAV0101"
FT                   /id="PRO_0000194628"
FT   DOMAIN          158..256
FT                   /note="HTH araC/xylS-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        175..196
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        223..246
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
SQ   SEQUENCE   745 AA;  87878 MW;  73AE9BAD975DD3C7 CRC64;
     MQRDYLIRVE TESMPDFKRL NGLMIGFVIK GEAHIYDENN MTQCNSGDIF IINHRDLYRF
     QLQQDGIICY IQFQMKYLAD KFDDAHCLYF HLTDATTTKN IHQLRNIMAR LVSTHIRHNE
     LSKLTEQQLV IQLLMHMIHY VPRTYHSNQS ILNDDKVNQV CDYIELHFHE DLSLSELSEY
     VGWSESHLSK KFTESLGVGF QHFLNTTRIE HAKLDLTYTD ETITDIALQN GFSSAASFAR
     TFKHFTHQTP KQYRGDRPAI TENQQSAQHN YHDRELILLL NDYIEEMNHF IEDIEKMNYK
     EIAFKPTNQQ LNQFNHIIQV GYLRNLLNTQ YQSQLLTCHH DFQVNEVLAY DVMPYIMKKL
     NAPFTYDAEI SNIFYDIDLC LDFLLDHNFS LTMHLNQYDS RDYIDAFKVF IHHVALHVSH
     RKDLKFNLYV TTLHTSLIEM IDYFKALFPN GGLYIHLDQA TERHLPLLKR LEPHINHFVF
     DANSNDAVDF NKMNDDEFKT ASQMIINKTN YLIDLMHRHN LKRPLILLNW NTLTGDTFIT
     NGEYFRGGII IEQLLKLSTK VEGIGYWLNY DLHVSHCRNE RDYMNSIELF HQYNGKRPVY
     FTALLFNKLT SNILYSDDTC IVTGTDSNFQ ILLYDAKHFN PYLALDNQMN MRATEMIHLN
     INALEDGMYK IKHFTLDKEN GALFNLWRKH HTIHGMDKDS IDYVNRMSFP KLEVYDIDIT
     DTLALNIKMI TNGIHLIEVK RYPSS