ID   Y1032_HAEIN             Reviewed;         268 AA.
AC   P44996;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator HI_1032;
GN   OrderedLocusNames=HI_1032;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
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DR   EMBL; L42023; AAC22692.1; -; Genomic_DNA.
DR   PIR; D64165; D64165.
DR   RefSeq; NP_439192.1; NC_000907.1.
DR   AlphaFoldDB; P44996; -.
DR   SMR; P44996; -.
DR   STRING; 71421.HI_1032; -.
DR   EnsemblBacteria; AAC22692; AAC22692; HI_1032.
DR   KEGG; hin:HI_1032; -.
DR   PATRIC; fig|71421.8.peg.1076; -.
DR   eggNOG; COG1414; Bacteria.
DR   HOGENOM; CLU_062618_7_1_6; -.
DR   OMA; RYPVRMY; -.
DR   PhylomeDB; P44996; -.
DR   BioCyc; HINF71421:G1GJ1-1072-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR   InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF09339; HTH_IclR; 1.
DR   Pfam; PF01614; IclR; 1.
DR   SMART; SM00346; HTH_ICLR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS51077; HTH_ICLR; 1.
DR   PROSITE; PS51078; ICLR_ED; 1.
PE   4: Predicted;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..268
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   HI_1032"
FT                   /id="PRO_0000201772"
FT   DOMAIN          15..77
FT                   /note="HTH iclR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00393"
FT   DOMAIN          92..265
FT                   /note="IclR-ED"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00394"
FT   DNA_BIND        37..56
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00393"
SQ   SEQUENCE   268 AA;  30580 MW;  AAAF3080ED39EA14 CRC64;
     MNIEVKMEKE KSLGNQALIR GLRLLDILSN YPNGCPLAKL AELANLNKST AHRLLQGLQN
     EGYVKPANAA GSYRLTIKCL SIGQKVLSSM NIIHVASPYL EQLNLKLGET INFSKREDDH
     AIMIYKLEPT NGMLKTRAYI GQYLKLYCSA MGKIFLAYEK KVDYLSHYWQ SHQREIKKLT
     RYTITELDDI KLELETIRQT AYAMDREENE LGVTCIACPI FDSFGQVEYA ISVSMSIYRL
     NKFGTDAFLQ EIRKTAEQIS LELGYENI