ID   Y1038_PYRHO             Reviewed;         291 AA.
AC   O58759;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=Probable ABC transporter permease protein PH1038;
GN   OrderedLocusNames=PH1038; ORFNames=PHAJ015;
OS   Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS   100139 / OT-3).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=70601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX   PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA   Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA   Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA   Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA   Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA   Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT   "Complete sequence and gene organization of the genome of a hyper-
RT   thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL   DNA Res. 5:55-76(1998).
CC   -!- FUNCTION: Probably part of a binding-protein-dependent transport system
CC       PH1036/38/39. Probably responsible for the translocation of the
CC       substrate across the membrane.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. MalFG subfamily. {ECO:0000305}.
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DR   EMBL; BA000001; BAA30136.1; -; Genomic_DNA.
DR   PIR; B71097; B71097.
DR   RefSeq; WP_010885125.1; NC_000961.1.
DR   AlphaFoldDB; O58759; -.
DR   SMR; O58759; -.
DR   STRING; 70601.3257453; -.
DR   EnsemblBacteria; BAA30136; BAA30136; BAA30136.
DR   GeneID; 1443360; -.
DR   KEGG; pho:PH1038; -.
DR   eggNOG; arCOG00157; Archaea.
DR   OMA; YKIVYFF; -.
DR   OrthoDB; 42250at2157; -.
DR   Proteomes; UP000000752; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..291
FT                   /note="Probable ABC transporter permease protein PH1038"
FT                   /id="PRO_0000060309"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        75..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        160..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        208..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        232..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        267..287
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          71..286
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   291 AA;  32640 MW;  0F72593880AC5BE2 CRC64;
     MRRNLTPFFF LLPALTLMVP FVIYPVFKTI YLSFFLGDKF VGLENYKNVL LSPDIVNLER
     FPTKSPPWGA LIHNIVWIAI HLPTTIFLGL GFALLLRKKE VKGSSIIKSI IFLGMVIPMV
     VGGLIIRFLF EEGAGVIPAF FKLIGIEKLA ITWTAYPQTA LFSVILGSIW IWTGFSMLMY
     SAGLASIPKD YYEAALIDGA NKFQIFRFVI WPLLRPITVV IVAMTLLWDL KIFDIVYVAT
     GGGPGGASMV LALQMWDYFA RSLNYNYAAV VAVLLTALTF IPALWLIKRR G