ID   Y104_MYCTO              Reviewed;         504 AA.
AC   P9WM60; L0T2G9; Q10898;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 41.
DE   RecName: Full=Uncharacterized protein MT0113;
GN   OrderedLocusNames=MT0113;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000516; AAK44335.1; -; Genomic_DNA.
DR   PIR; H70751; H70751.
DR   RefSeq; WP_003899813.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WM60; -.
DR   SMR; P9WM60; -.
DR   EnsemblBacteria; AAK44335; AAK44335; MT0113.
DR   KEGG; mtc:MT0113; -.
DR   PATRIC; fig|83331.31.peg.118; -.
DR   HOGENOM; CLU_041783_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; -; 1.
DR   Gene3D; 3.40.50.1480; -; 1.
DR   InterPro; IPR042172; Adenosylhomocyst_ase-like_sf.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..504
FT                   /note="Uncharacterized protein MT0113"
FT                   /id="PRO_0000427360"
FT   TRANSMEM        146..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        196..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        330..350
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   BINDING         372..492
FT                   /ligand="a nucleoside 3',5'-cyclic phosphate"
FT                   /ligand_id="ChEBI:CHEBI:58464"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00060"
SQ   SEQUENCE   504 AA;  53451 MW;  3FCF8A42EE75009F CRC64;
     MTPVTTFPLV DAILAGRDRN LDGVILIAAQ HLLQTTHAML RSLFRVGLDP RNVAVIGKCY
     STHPGVVDAM RADGIYVDDC SDAYAPHESF DTQYTRHVER FFAESWARLT AGRTARVVLL
     DDGGSLLAVA GAMLDASADV IGIEQTSAGY AKIVGCALGF PVINIARSSA KLLYESPIIA
     ARVTQTAFER TAGIDSSAAI LITGAGAIGT ALADVLRPLH DRVDVYDTRS GCMTPIDLPN
     AIGGYDVIIG ATGATSVPAS MHELLRPGVL LMSASSSDRE FDAVALRRRT TPNPDCHADL
     RVADGSVDAT LLNSGFPVNF DGSPMCGDAS MALTMALLAA AVLYASVAVA DEMSSDHPHL
     GLIDQGDIVA SFLNIDVPLQ ALSRLPLLSI DGYRRLQVRS GYTLFRQGER ADHFFVIESG
     ELEALVDGKV ILRLGAGDHF GEACLLGGMR RIATVRACEP SVLWELDGKA FGDALHGDAA
     MREIAYGVAR TRLMHAGASE SLMV