ID   Y1051_HAEIN             Reviewed;         614 AA.
AC   Q57180; O05043;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 136.
DE   RecName: Full=Uncharacterized ABC transporter ATP-binding protein HI_1051;
GN   OrderedLocusNames=HI_1051;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR   EMBL; L42023; AAC22709.1; -; Genomic_DNA.
DR   PIR; A64180; A64180.
DR   RefSeq; NP_439210.1; NC_000907.1.
DR   RefSeq; WP_005686318.1; NC_000907.1.
DR   AlphaFoldDB; Q57180; -.
DR   SMR; Q57180; -.
DR   STRING; 71421.HI_1051; -.
DR   PRIDE; Q57180; -.
DR   EnsemblBacteria; AAC22709; AAC22709; HI_1051.
DR   KEGG; hin:HI_1051; -.
DR   PATRIC; fig|71421.8.peg.1096; -.
DR   eggNOG; COG1132; Bacteria.
DR   HOGENOM; CLU_000604_62_3_6; -.
DR   OMA; SHWVMWE; -.
DR   PhylomeDB; Q57180; -.
DR   BioCyc; HINF71421:G1GJ1-1090-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0034040; F:ATPase-coupled lipid transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   Gene3D; 1.20.1560.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011527; ABC1_TM_dom.
DR   InterPro; IPR036640; ABC1_TM_sf.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR039421; Type_1_exporter.
DR   PANTHER; PTHR24221; PTHR24221; 1.
DR   Pfam; PF00664; ABC_membrane; 1.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF90123; SSF90123; 1.
DR   PROSITE; PS50929; ABC_TM1F; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..614
FT                   /note="Uncharacterized ABC transporter ATP-binding protein
FT                   HI_1051"
FT                   /id="PRO_0000093203"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        157..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        178..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          43..330
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          364..603
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         397..404
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   614 AA;  68399 MW;  306BBA9646921EA0 CRC64;
     MFNKIFSWFE NRLNPYPESN PTTPKKGLFR FIWSSITGMK GWIFLLAILT VGTGVMEAVL
     FQFMGTLVDW LGTFTPERLW QEKSHLLIGM AALLLISIVW GFLASAVHLQ TLQGVFPMRL
     RWNFHRLMLG QSLSFYQDEF AGRVSAKVMQ TALAVRDTVL TLANMFVYVL VYFITSGVVL
     VALDSWFLLP FITWIILFGL ILRTLIPKLS KTAQRQADAR SLMTGRITDA YSNIATVKLF
     SHGSREATYA KRSMQDFMVT VHAQMRLATS LDTLTYATNI LLTLSTAILG IILWKNGQVG
     VGAIATATAM ALRVNGLSRW IMWESARLFE NIGTVNDGMN TLTKPHTIVD KPQASPLQVK
     QGEIKFNDIT FAYDPTKPLL NHFNLTIKPG EKVGLIGRSG AGKSTIVNLL LRFYEAQQGE
     ITIDGQNVLN VQQESLRRQI GLVTQDTSLL HRSVRDNIIY GRPNATDEEM VLAAERAEAA
     DFIPFLSDSQ GRKGYDAHVG ERGVKLSGGQ RQRIAIARVM LKDAPILLLD EATSALDSEV
     EVAIQESLDK MMENKTVIAI AHRLSTIAAM DRLIVLDKGQ IVEQGTHAEL LELNGLYAKL
     WNHQSGGFLS ESAE