ID   Y1058_MYCA1             Reviewed;         304 AA.
AC   A0QBM5;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_1058;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAV_1058;
OS   Mycobacterium avium (strain 104).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=243243;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=104;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000479; ABK65650.1; -; Genomic_DNA.
DR   RefSeq; WP_011723913.1; NC_008595.1.
DR   AlphaFoldDB; A0QBM5; -.
DR   SMR; A0QBM5; -.
DR   EnsemblBacteria; ABK65650; ABK65650; MAV_1058.
DR   KEGG; mav:MAV_1058; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; TYPGEHT; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000001574; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..304
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAV_1058"
FT                   /id="PRO_0000361100"
FT   BINDING         128
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         157..158
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   304 AA;  32365 MW;  F98AB01A44029F61 CRC64;
     MTRSEGDTWN LASSVGATAT MVAAARAAAT RRPRPVLTDE YAEPLVRAVG LDVFTKLASG
     ELDPDDLERD VGFARMVDTF AARGRFYDDY FAAAGKAGLR QVVIVASGLD ARPYRLSWPA
     GTTVYEIDQP EVIAFKTATL SRIGAAPTAE LRTIGIDLRQ DWPAALQDAG FDAAQPTAWL
     AEGVLIGFLP PEAEVRLLDS ITPLSAEGSR FAADYGSLND ASQASTEQAR RTTEGWRRRG
     LDMDIAALTY PGKHTDVAAH LGADGWATTT FGLADLFAAA GLPELTEAEQ GPAATLSFVR
     AIKS