ID   Y105_MYCBO              Reviewed;         661 AA.
AC   P64690; A0A1R3XUC4; Q10897; X2BE16;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Uncharacterized protein Mb0105;
GN   OrderedLocusNames=BQ2027_MB0105;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To M.leprae ML1998. {ECO:0000305}.
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DR   EMBL; LT708304; SIT98512.1; -; Genomic_DNA.
DR   RefSeq; NP_853773.1; NC_002945.3.
DR   RefSeq; WP_003900808.1; NC_002945.4.
DR   AlphaFoldDB; P64690; -.
DR   PATRIC; fig|233413.5.peg.117; -.
DR   OMA; YVVYFTP; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR019108; Caa3_assmbl_CtaG-rel.
DR   InterPro; IPR008457; Cu-R_CopD.
DR   Pfam; PF09678; Caa3_CtaG; 1.
DR   Pfam; PF05425; CopD; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..661
FT                   /note="Uncharacterized protein Mb0105"
FT                   /id="PRO_0000103673"
FT   TRANSMEM        27..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        116..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        179..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        251..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        279..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        313..333
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        369..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        396..416
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        435..455
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        488..508
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        519..539
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        552..572
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        599..619
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   661 AA;  70357 MW;  68B3BB57D0066C57 CRC64;
     MGTHGATKSA TSAVPTPRSN SMAMVRLAIG LLGVCAVVAA FGLVSGARRY AEAGNPYPGA
     FVSVAEPVGF FAASLAGALC LGALIHVVMT AKPEPDGLID AAAFRIHLLA ERVSGLWLGL
     AATMVVIQAA HDTGVGPARL LASGALSDSV AASEMARGWI VAAICALVVA TALRLYTRWL
     GHVVLLVPTV LAVVATAVTG NPGQGPDHDY ATSAAIVFAV AFATLTGLKI AAALAGTTPS
     RAVLVTQVTC GALALAYGAM LLYLFIPGWA VDSDFARLGL LAGVILTSVW LFDCWRLLVR
     PPHAGRRRGG GSGAALAMMA AMASIAAMAV MTAPRFLTHA FTAWDVFLGY ELPQPPTIAR
     VLTVWRFDSL IGAAGVVLAI GYAAGFAALR RRGNSWPVGR LIAWLTGCAA LVFTSGSGVR
     AYGSAMFSVH MAEHMTLNMF IPVLLVLGGP VTLALRVLPV TGDGRPPGAR EWLTWLLHSR
     VTTFLSHPIT AFVLFVASPY IVYFTPLFDT FVRYHWGHEF MAIHFLVVGY LFYWAIIGID
     PGPRRLPYPG RIGLLFAVMP FHAFFGIALM TMSSTVGATF YRSVNLPWLS SIIADQHLGG
     GIAWSLTELP VIMVIVALVT QWARQDRRVA SREDRHADSD YADDELEAYN AMLRELSRMR
     R