ID   Y105_RICPR              Reviewed;         672 AA.
AC   Q9ZE43;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Uncharacterized protein RP105;
DE   Flags: Precursor;
GN   OrderedLocusNames=RP105;
OS   Rickettsia prowazekii (strain Madrid E).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=272947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Madrid E;
RX   PubMed=9823893; DOI=10.1038/24094;
RA   Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T.,
RA   Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H.,
RA   Kurland C.G.;
RT   "The genome sequence of Rickettsia prowazekii and the origin of
RT   mitochondria.";
RL   Nature 396:133-140(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TrbL/VirB6 family. {ECO:0000305}.
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DR   EMBL; AJ235270; CAA14574.1; -; Genomic_DNA.
DR   PIR; G71719; G71719.
DR   RefSeq; NP_220497.1; NC_000963.1.
DR   RefSeq; WP_010886211.1; NC_000963.1.
DR   AlphaFoldDB; Q9ZE43; -.
DR   STRING; 272947.RP105; -.
DR   EnsemblBacteria; CAA14574; CAA14574; CAA14574.
DR   KEGG; rpr:RP105; -.
DR   PATRIC; fig|272947.5.peg.107; -.
DR   eggNOG; COG3704; Bacteria.
DR   HOGENOM; CLU_027273_0_0_5; -.
DR   OMA; GGADKCQ; -.
DR   Proteomes; UP000002480; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030255; P:protein secretion by the type IV secretion system; IEA:InterPro.
DR   InterPro; IPR007688; Conjugal_tfr_TrbL/VirB6.
DR   Pfam; PF04610; TrbL; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..672
FT                   /note="Uncharacterized protein RP105"
FT                   /id="PRO_0000269210"
FT   TRANSMEM        226..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        254..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        410..430
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        436..456
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        469..489
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        562..582
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          363..384
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          628..672
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        628..649
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   672 AA;  73713 MW;  BE5CE2ABF273F691 CRC64;
     MKTLKVLKIF IIVYISSVSL ESFAGFGESC SNLPITSDGY LETYTAYGYI IRSIDMKDPR
     GNCNPSTSSI TFCFKNVEGS ASPCTIYTLN EGDTRKISDL STDNNPDLGA NTVLKNIVLT
     VKKFGNDLCL AMPTSRGPMP VACKSLSVTP TATKPKDENC NIGKSCYTGA NYSQSLINFS
     GLAVQCLSET LNKIFFTGSS CSAQDQNSRI THLASFATFQ GYLKRIIGAA LILYTMFFAF
     NMALNKEYAT TEKITLFIIK FLFVVYFSIG LGPLDFSGGQ PVKENGMLKY GLPLLTGAAP
     DFAGMIFNAA GSRGLCQFDN TKYKDGYKFY GLWDAIDCRI GYYLGLDLLY NIDKNGILGR
     PVSNGTSGNN KPIPNFDPDG KKDRPHDLSK AGALRFFTVM FGFFMSGHVI ILVAGMVFSV
     IFLSILLYFI THYLVCMVTI YVMTYISPIF IPMVLFTRTK AYFDGWLKVC ISCALQPAVV
     AGFIALLITM YDSAIFKNCE FLRYDYEKGD IRFSTFELRL PSIDADKCQE SFGYKMLKYY
     AGEGWEEHLL ILFPIKSIVR DVVSILAELL CVLIFSVIFY YFSKSIGRFA ADLTNGPNMD
     AVTASPTKIV DLVKKGAAFL KDASVHEHGK SSLGDKPDIG NKRKDGAQQG EDAVNSSGGE
     VADLASGSGG GK