ID   Y1061_MYCSK             Reviewed;         308 AA.
AC   A1UBR7;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase Mkms_1061;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=Mkms_1061;
OS   Mycobacterium sp. (strain KMS).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; unclassified Mycobacterium.
OX   NCBI_TaxID=189918;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KMS;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D.,
RA   Richardson P.;
RT   "Complete sequence of chromosome of Mycobacterium sp. KMS.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000518; ABL90275.1; -; Genomic_DNA.
DR   RefSeq; WP_011558460.1; NC_008705.1.
DR   AlphaFoldDB; A1UBR7; -.
DR   SMR; A1UBR7; -.
DR   STRING; 189918.Mkms_1061; -.
DR   EnsemblBacteria; ABL90275; ABL90275; Mkms_1061.
DR   KEGG; mkm:Mkms_1061; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; DFFTRWV; -.
DR   OrthoDB; 847145at2; -.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..308
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase Mkms_1061"
FT                   /id="PRO_0000361212"
FT   BINDING         133
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         162..163
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   308 AA;  33234 MW;  E7096FFB7A2C2333 CRC64;
     MARTDNDTWD LASSVGATAT MVAAARAVAT RAPDAVIDDP FAEPLVRAVG VDFFTRLATG
     DLTPTDLDPD ATGGAGNMDR FADGMAARTR FFDDFFSDAA DAGVRQAVIL ASGLDSRAYR
     LPWPAGTVVF EIDQPGVITF KSDTLARLGA KPTAVHRTVP VDLRDDWIGA LEAAGFDRTE
     PSAWIAEGLF GYLPPEAQDR LLDQITELSP PGSRLAVEGV VSSPDADDEQ IRERMQAVRD
     QWRQFGFDLD FSELVYTGER AEVAAYLGDR GWRTDSITAT ALLEKCGLQS AEDSSANFAD
     VRYVTAVK