ID   Y1063_STAHJ             Reviewed;         329 AA.
AC   Q4L7K3;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=UPF0421 protein SH1063;
GN   OrderedLocusNames=SH1063;
OS   Staphylococcus haemolyticus (strain JCSC1435).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=279808;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCSC1435;
RX   PubMed=16237012; DOI=10.1128/jb.187.21.7292-7308.2005;
RA   Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y.,
RA   Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C.,
RA   Hiramatsu K.;
RT   "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the
RT   extreme plasticity of its genome and the evolution of human-colonizing
RT   staphylococcal species.";
RL   J. Bacteriol. 187:7292-7308(2005).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0421 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AP006716; BAE04372.1; -; Genomic_DNA.
DR   RefSeq; WP_011275368.1; NC_007168.1.
DR   AlphaFoldDB; Q4L7K3; -.
DR   SMR; Q4L7K3; -.
DR   STRING; 279808.SH1063; -.
DR   EnsemblBacteria; BAE04372; BAE04372; SH1063.
DR   GeneID; 58062762; -.
DR   KEGG; sha:SH1063; -.
DR   eggNOG; COG4129; Bacteria.
DR   HOGENOM; CLU_067028_0_0_9; -.
DR   OMA; ANVMEEW; -.
DR   OrthoDB; 1974930at2; -.
DR   Proteomes; UP000000543; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010343; ArAE_1.
DR   Pfam; PF06081; ArAE_1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..329
FT                   /note="UPF0421 protein SH1063"
FT                   /id="PRO_0000283025"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        108..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        131..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   329 AA;  37545 MW;  3B7544355510AAC5 CRC64;
     MDKWYKKIIG ARTIKTGLAT FLTSLFCLML DLTPIFAILT AIVTIEPTAK ASLKKGYRRL
     PATVIGALFA VLFTFIFGDP SALTYTFSAL FTILVCTKLN LQVGTTVAVL TSVAMIPGIH
     DAYLFNFFSR LLTALIGLVT AGLVNFIVLP PKYYQQIEDN LTQSEYKMYE LFSSRCNELL
     LGKFDSDHSN DLLNKLMGVI NKTETLTGYQ KDELRYHKNK EDEWKRLKNI SNRSYIDRLL
     ATHLSNIIYL PKHIHLVFTP EEKIAIIKIS NSVNNIIKSN HFEPHRSSAS TLKSSVKRLE
     EFDQNQIKSH VIYEILLIYK LLDSRYNDK