ID   Y1072_MYCSJ             Reviewed;         297 AA.
AC   A3PVF2;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase Mjls_1072;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=Mjls_1072;
OS   Mycobacterium sp. (strain JLS).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; unclassified Mycobacterium.
OX   NCBI_TaxID=164757;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JLS;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Anderson A.J.,
RA   Sims R.C., Richardson P.;
RT   "Complete sequence of Mycobacterium sp. JLS.";
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000580; ABN96879.1; -; Genomic_DNA.
DR   AlphaFoldDB; A3PVF2; -.
DR   SMR; A3PVF2; -.
DR   STRING; 164757.Mjls_1072; -.
DR   KEGG; mjl:Mjls_1072; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; TEHVPDP; -.
DR   BioCyc; MSP164757:G1G8C-1085-MON; -.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..297
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase Mjls_1072"
FT                   /id="PRO_0000361204"
FT   BINDING         124
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         153..154
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   297 AA;  32665 MW;  ADA6A97B699DD54F CRC64;
     MARSDEDSWD LASSVGATAT MVAAARAVAS RGPEALIDDP YADALVRAVG VEYFVKLLDG
     EITLEADNAA MLAVMTDVMA VRTRFFDDFF LSSGLPQAVI LASGLDARAY RLPWPSGSVV
     YEIDQPEVIE FKTRTLADLG ASPAAELRTV AIDLRDDWPR ALRDRGFDPT APTAWIAEGL
     LIYLPPDAQD RLFDNITALS APGSRLATEF HPDAGARIGA SSQRMAEEWR RHGLDLDMAD
     LFYDGERNPV VDYLRERGWE VEARSRPDMF AHYGRPFPTG EAVEALRQSL AVTATRR