ID   Y1073_MYCSJ             Reviewed;         308 AA.
AC   A3PVF3;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase Mjls_1073;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=Mjls_1073;
OS   Mycobacterium sp. (strain JLS).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; unclassified Mycobacterium.
OX   NCBI_TaxID=164757;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JLS;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Anderson A.J.,
RA   Sims R.C., Richardson P.;
RT   "Complete sequence of Mycobacterium sp. JLS.";
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000580; ABN96880.1; -; Genomic_DNA.
DR   AlphaFoldDB; A3PVF3; -.
DR   SMR; A3PVF3; -.
DR   STRING; 164757.Mjls_1073; -.
DR   KEGG; mjl:Mjls_1073; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; DFFTRWV; -.
DR   BioCyc; MSP164757:G1G8C-1086-MON; -.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..308
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase Mjls_1073"
FT                   /id="PRO_0000361205"
FT   BINDING         133
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         162..163
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   308 AA;  33264 MW;  31D8DC443B1E2321 CRC64;
     MARTDNDTWD LASSVGATAT MVAAARAVAT RAPDAVIDDP FAEPLVRAVG VDFFTRLATG
     DLTPTDLDPD ATGGAGNMDR FADGMAARTR FFDDFFSDAA DAGVRQAVIL ASGLDSRAYR
     LPWPAGTVVF EIDQPGVITF KSDTLARLGA KPTADHRTVP VDLRDDWIGA LEAAGFDRTE
     PSAWIAEGLF GYLPPEAQDR LLDQITELSP PGSRLAVEGV VSSPDADDEQ IRERMQAVRD
     QWRQFGFDLD FSELVYTGER AEVAAYLGER GWRTDSITAT ALLEKCGLQS AEDSSANFAD
     VRYVTAVK