ID   Y107_STAAR              Reviewed;         745 AA.
AC   Q6GKK1;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator SAR0107;
GN   OrderedLocusNames=SAR0107;
OS   Staphylococcus aureus (strain MRSA252).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282458;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MRSA252;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
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DR   EMBL; BX571856; CAG39133.1; -; Genomic_DNA.
DR   RefSeq; WP_001188463.1; NC_002952.2.
DR   AlphaFoldDB; Q6GKK1; -.
DR   SMR; Q6GKK1; -.
DR   KEGG; sar:SAR0107; -.
DR   HOGENOM; CLU_017624_1_0_9; -.
DR   OMA; TNGRFFR; -.
DR   Proteomes; UP000000596; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR037923; HTH-like.
DR   InterPro; IPR018060; HTH_AraC.
DR   InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR   Pfam; PF12833; HTH_18; 1.
DR   PRINTS; PR00032; HTHARAC.
DR   SMART; SM00342; HTH_ARAC; 1.
DR   SUPFAM; SSF46689; SSF46689; 2.
DR   SUPFAM; SSF51215; SSF51215; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE   4: Predicted;
KW   DNA-binding; Repeat; Transcription; Transcription regulation.
FT   CHAIN           1..745
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   SAR0107"
FT                   /id="PRO_0000194630"
FT   DOMAIN          158..256
FT                   /note="HTH araC/xylS-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        175..196
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        223..246
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
SQ   SEQUENCE   745 AA;  87812 MW;  201366A3D2240BD4 CRC64;
     MQRDYLIRVE TESMLDFKRL NGLMIGFVIK GEAHIYDENN MTQCNSGDIF IINHRDLYRF
     QLQQDGIICY IQFQMKYLAD KFDDVHCLYF HLTDATTTKN IHQLRNIMAR LVSTHIRHNE
     LSKLTEQQLV IQLLMHMIHY VPRTYHSNQS ILNDDKVNQV CDYIELHFHE DLSLSELSEY
     VGWSESHLSK KFAESLGVGF QHFLNTTRIE HAKLDLTYTD ETITDIALQN GFSSAASFAR
     TFKHFTHQTP KQYRGDRPAI TENQQSAQHN YHDRELILLL NDYIEEMNHF IEDIEKVNYK
     EITFQPTNHQ LNQFNHIIQV GYLRNLLNTQ YQSQLLTCHS DFQVNEVLAY DVMPYIMKKL
     NAPFTYDAEI SNIFYDIDLC LDFLLDHNFS LTMHLNQYDS RDYIDAFKVF IHHVALHVSH
     RKDLKFNLYV TTLHNSLIEM IDYFKALFPN GGLYVHLDQA TERHLPLLKR LEPHIDHFVF
     DANSNDAVDF NKMNDDEFKT ASQMIINKTN YLIDLMHRHH LKRPLILLNW NTLTGDTFIT
     NGEYFRGGII IEQLLKLSSK VEGIGYWLNY DLHVSHCKNE RDYMNSIELF HQYNGKRPVY
     FTALLFNKLT SNILYSDDTC IVTGTDSNFQ ILLYDAKHFN PYLALDNQMN MRATEMIHLN
     INALEEGIYK IKHFTLDKEN GALFNLWRKH HTIHGMDKDS IDYVNRMSFP KLEVYDIDVT
     DTLALNIKMI TNGIHLIEVK RYPSS