ID   Y1081_THENE             Reviewed;         113 AA.
AC   O86949;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Putative anti-sigma factor antagonist TM1081 homolog;
DE   AltName: Full=ORF3;
OS   Thermotoga neapolitana.
OC   Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
OX   NCBI_TaxID=2337;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Z2706-MC24;
RA   Zverlov V.V.;
RL   Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: In the phosphorylated form it could act as an anti-anti-sigma
CC       factor that counteracts an anti-sigma factor and thus releases a sigma
CC       factor from inhibition. {ECO:0000250}.
CC   -!- PTM: Phosphorylated on a serine residue. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the anti-sigma-factor antagonist family.
CC       {ECO:0000305}.
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DR   EMBL; AJ007446; CAA07514.1; -; Genomic_DNA.
DR   AlphaFoldDB; O86949; -.
DR   SMR; O86949; -.
DR   GO; GO:0043856; F:anti-sigma factor antagonist activity; IEA:InterPro.
DR   Gene3D; 3.30.750.24; -; 1.
DR   InterPro; IPR003658; Anti-sigma_ant.
DR   InterPro; IPR002645; STAS_dom.
DR   InterPro; IPR036513; STAS_dom_sf.
DR   Pfam; PF01740; STAS; 1.
DR   SUPFAM; SSF52091; SSF52091; 1.
DR   TIGRFAMs; TIGR00377; ant_ant_sig; 1.
DR   PROSITE; PS50801; STAS; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein.
FT   CHAIN           1..113
FT                   /note="Putative anti-sigma factor antagonist TM1081
FT                   homolog"
FT                   /id="PRO_0000194207"
FT   DOMAIN          1..110
FT                   /note="STAS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00198"
FT   MOD_RES         55
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   113 AA;  12862 MW;  6E22BE280624117B CRC64;
     MFPYKIVEDV VILMPNKELN IENAHLFKKW VFDEFLNKGY NKILLVLSDV ESIDSFSLGV
     IVNILKSVSS VGGFFALVSP NERVERVLSI TNLDRIVKIY DTISEALEEV QGR