ID   Y108_RICPR              Reviewed;        1155 AA.
AC   Q9ZE40;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Uncharacterized lipoprotein RP108;
DE   Flags: Precursor;
GN   OrderedLocusNames=RP108;
OS   Rickettsia prowazekii (strain Madrid E).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=272947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Madrid E;
RX   PubMed=9823893; DOI=10.1038/24094;
RA   Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T.,
RA   Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H.,
RA   Kurland C.G.;
RT   "The genome sequence of Rickettsia prowazekii and the origin of
RT   mitochondria.";
RL   Nature 396:133-140(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Multi-pass membrane protein {ECO:0000305}. Cell
CC       membrane {ECO:0000255|PROSITE-ProRule:PRU00303}; Lipid-anchor
CC       {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the TrbL/VirB6 family. {ECO:0000305}.
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DR   EMBL; AJ235270; CAA14577.1; -; Genomic_DNA.
DR   PIR; B71720; B71720.
DR   RefSeq; NP_220500.1; NC_000963.1.
DR   RefSeq; WP_010886214.1; NC_000963.1.
DR   AlphaFoldDB; Q9ZE40; -.
DR   SMR; Q9ZE40; -.
DR   STRING; 272947.RP108; -.
DR   EnsemblBacteria; CAA14577; CAA14577; CAA14577.
DR   KEGG; rpr:RP108; -.
DR   PATRIC; fig|272947.5.peg.110; -.
DR   eggNOG; COG1340; Bacteria.
DR   eggNOG; COG3704; Bacteria.
DR   HOGENOM; CLU_275941_0_0_5; -.
DR   OMA; ECIDERY; -.
DR   Proteomes; UP000002480; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030255; P:protein secretion by the type IV secretion system; IEA:InterPro.
DR   InterPro; IPR007688; Conjugal_tfr_TrbL/VirB6.
DR   Pfam; PF04610; TrbL; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           20..1155
FT                   /note="Uncharacterized lipoprotein RP108"
FT                   /id="PRO_0000269912"
FT   TRANSMEM        289..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        395..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        424..444
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        459..479
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   LIPID           20
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           20
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   1155 AA;  132311 MW;  E55EA3CE29F7ACCB CRC64;
     MKKNIFITSL LILLLLLSSC TGDTCIDPDD FGFITFNVSS RYNPGEITSR HEGDQVTPWR
     DSAYKVNGYP LTIMVRPWNY ILGDKNTSGQ LSAWCPWYGQ KNNTTTLAPF CVKLQPCTFW
     DNARFDMCTP NPENRNDAMI SNPPCIMTDG VGLYFLIAAK NTDPNISPDS QRRPQGITKH
     LGELTSSVGY EFYSISSTGQ FLKAGGINYQ YNGEDKSKYA QSPLYFKIID KFYDDNSGQY
     RLVIKSGVSD TRPDPLQFLT DLIKKVLFGK DGMIKKTYQQ IIDTPGYKIS VSAILTLYIM
     FTVLSFLIGN INLTHVELII RIFKISIISI LLSTDKAWTF FHDYLFVFFI DGVQQILQII
     NEAAATGPGS QSLLGLLIST QTLSKLFSLL FVDWLGFIYI ILYLIALYFI FFLIFKATII
     YLTALITIGM IIIMGPIFIC FMLFNITRSL FENWLRQLIS YALQPIILFA GIAFISMIIR
     TEIYSTLGFG VCKHDFPNLG PINEIFGSFL EDIDPSLGNS IFYWWFPVPM KGGINNFHKA
     KILVPNDHIV VDASCKNDHD KCKHCAAYEC IDERYIELPF LDLVKDSTRI NNFINGKFVQ
     LDGILLIFVS IYLLSKFNDT AVSTAQFIAG TSGNLTDIQK VNQQSYESLS QQINRPLNYV
     AQAVSAPVTS RISAGTEQAS MFFAEKFENM MMERLEKQAL SSSANKAVQN EVKRKYGIDS
     KDVKMNAIKD YEDGISGLLK NLPKRNELKV KELSQMKFIQ LRDKISANKY DVQDYAALSK
     EQKTELDKLL KDANLRALAS EANFTKDYQE AYKQAHQEMS GRGIGLFGKN IGVLRSWQEM
     EHRVNVKRKL KEEKRIGIGE KIYAGYTGIK RAALTKILGK DLRDAYEGNL TSAEWHDFEY
     NDPRLRTYSE KLKDDEKARE YEELRMHINK ETIAVQADIL SPEYLVKLEK AGRQSDVEYY
     QGLAQKQLIH DVHSRLFEEG EPVMMGDRFM REKATDSQMR DMIDNAHKKY AELIDVDRYT
     RRQEYYDIIH EKAKENLEQT YKELKDHFKS DNISIEEMPS LIAQKVKDTN TGSEIDKKIT
     EEINNFNTDV KNYEYSTAVL NKIEDRKQAI MNEVNAQIDK INKYRASAKM EQYVKPILNE
     GRKLRTLEDH LKNMT