Y1092_MYCBO
ID Y1092_MYCBO Reviewed; 360 AA.
AC P67099; A0A1R3XX89; O53411; X2BGK7;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 25-MAY-2022, entry version 82.
DE RecName: Full=Uncharacterized NTE family protein Mb1092c;
GN OrderedLocusNames=BQ2027_MB1092C;
OS Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=233413;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT "The complete genome sequence of Mycobacterium bovis.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA Robbe-Austerman S., Gordon S.V.;
RT "Updated reference genome sequence and annotation of Mycobacterium bovis
RT AF2122/97.";
RL Genome Announc. 5:E00157-E00157(2017).
CC -!- SIMILARITY: Belongs to the NTE family. {ECO:0000305}.
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DR EMBL; LT708304; SIT99691.1; -; Genomic_DNA.
DR RefSeq; NP_854747.1; NC_002945.3.
DR RefSeq; WP_003405642.1; NC_002945.4.
DR AlphaFoldDB; P67099; -.
DR SMR; P67099; -.
DR EnsemblBacteria; SIT99691; SIT99691; BQ2027_MB1092C.
DR PATRIC; fig|233413.5.peg.1190; -.
DR OMA; CSMPGLL; -.
DR Proteomes; UP000001419; Chromosome.
DR GO; GO:0004622; F:lysophospholipase activity; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR001423; LysoPLipase_patatin_CS.
DR InterPro; IPR002641; PNPLA_dom.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; SSF52151; 1.
DR PROSITE; PS51635; PNPLA; 1.
DR PROSITE; PS01237; UPF0028; 1.
PE 3: Inferred from homology;
KW Hydrolase; Lipid degradation; Lipid metabolism.
FT CHAIN 1..360
FT /note="Uncharacterized NTE family protein Mb1092c"
FT /id="PRO_0000172535"
FT DOMAIN 19..179
FT /note="PNPLA"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
FT REGION 251..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 50..54
FT /note="GXSXG"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
FT MOTIF 166..168
FT /note="DGA/G"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
FT ACT_SITE 52
FT /note="Nucleophile"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
FT ACT_SITE 166
FT /note="Proton acceptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
SQ SEQUENCE 360 AA; 37523 MW; F08C30CE6096D0F6 CRC64;
MPAPAALRVR GSSSPRVALA LGSGGARGYA HIGVIQALRE RGYDIVGIAG SSMGAVVGGV
HAAGRLDEFA HWAKSLTQRT ILRLLDPSIS AAGILRAEKI LDAVRDIVGP VAIEQLPIPY
TAVATDLLAG KSVWFQRGPL DAAIRASIAI PGVIAPHEVD GRLLADGGIL DPLPMAPIAG
VNADLTIAVS LNGSEAGPAR DAEPNVTAEW LNRMVRSTSA LFDVSAARSL LDRPTARAVL
SRFGAAAAES DSWSQAPEIE QRPAGPPADR EEAADTPGLP KMGSFEVMNR TIDIAQSALA
RHTLAGYPAD LLIEVPRSTC RSLEFHRAVE VIAVGRALAT QALEAFEIDD DESAAATIEG
