ID   Y1099_STRP8             Reviewed;          61 AA.
AC   P67534; Q99ZP7;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Probable tautomerase spyM18_1099;
DE            EC=5.3.2.-;
GN   OrderedLocusNames=spyM18_1099;
OS   Streptococcus pyogenes serotype M18 (strain MGAS8232).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=186103;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGAS8232;
RX   PubMed=11917108; DOI=10.1073/pnas.062526099;
RA   Smoot J.C., Barbian K.D., Van Gompel J.J., Smoot L.M., Chaussee M.S.,
RA   Sylva G.L., Sturdevant D.E., Ricklefs S.M., Porcella S.F., Parkins L.D.,
RA   Beres S.B., Campbell D.S., Smith T.M., Zhang Q., Kapur V., Daly J.A.,
RA   Veasy L.G., Musser J.M.;
RT   "Genome sequence and comparative microarray analysis of serotype M18 group
RT   A Streptococcus strains associated with acute rheumatic fever outbreaks.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:4668-4673(2002).
CC   -!- SIMILARITY: Belongs to the 4-oxalocrotonate tautomerase family.
CC       {ECO:0000305}.
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DR   EMBL; AE009949; AAL97721.1; -; Genomic_DNA.
DR   RefSeq; WP_002984671.1; NC_003485.1.
DR   AlphaFoldDB; P67534; -.
DR   SMR; P67534; -.
DR   GeneID; 57852627; -.
DR   KEGG; spm:spyM18_1099; -.
DR   HOGENOM; CLU_148073_5_1_9; -.
DR   OMA; HIMINDM; -.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006725; P:cellular aromatic compound metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.429.10; -; 1.
DR   InterPro; IPR004370; 4-oxalocrotonate_tautomerase.
DR   InterPro; IPR014347; Tautomerase/MIF_sf.
DR   Pfam; PF01361; Tautomerase; 1.
DR   SUPFAM; SSF55331; SSF55331; 1.
PE   3: Inferred from homology;
KW   Isomerase.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..61
FT                   /note="Probable tautomerase spyM18_1099"
FT                   /id="PRO_0000209558"
FT   ACT_SITE        2
FT                   /note="Proton acceptor; via imino nitrogen"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   61 AA;  7055 MW;  689FE80C7CC05754 CRC64;
     MPFVTIDLFE GRSQEQKNQL AREVTEVVSR IAKAPKENIH VFINDMPEGT YYPQGEMKQK
     S