ID   Y1101_MYCTO             Reviewed;         385 AA.
AC   P9WFM2; L0T7A7; O53449;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Putative transport protein MT1133;
GN   OrderedLocusNames=MT1133;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC       family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK45391.1; -; Genomic_DNA.
DR   PIR; C70897; C70897.
DR   RefSeq; WP_003898727.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WFM2; -.
DR   EnsemblBacteria; AAK45391; AAK45391; MT1133.
DR   GeneID; 45425075; -.
DR   KEGG; mtc:MT1133; -.
DR   PATRIC; fig|83331.31.peg.1223; -.
DR   HOGENOM; CLU_041771_2_3_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002549; AI-2E-like.
DR   PANTHER; PTHR21716; PTHR21716; 1.
DR   Pfam; PF01594; AI-2E_transport; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..385
FT                   /note="Putative transport protein MT1133"
FT                   /id="PRO_0000428514"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        66..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        159..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        218..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        241..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        263..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        319..339
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   385 AA;  41717 MW;  7468D37557C66B10 CRC64;
     MNTEFTLTQK RALAILTLIA LLFGAYFLRN YFVLIVVAAV GAYLFTPLFK WFTKRFNTGL
     SAACTLLSAL AAVVVPVGAL VGLAIVQIAR MVDSVADWVR TTDLSTLGDK ILQFVNGLFD
     RVPFLHITVT ADALRKAMIS VAQNVGEWLL HFLRDAAGSL AGVITSAIIF VYVFVALLVN
     REKLRTLIGQ LNPLGEDVTD LYLQKMGSMV RGTVNGQFVI AACQGVAGAA SIYIAGFHHG
     FFIFAIVLTA LSIIPLGGGI VTIPFGIGMI FYGNIAGGIF VLLWHLLVVT NIDNVLRPIL
     VPRDARLNSA LMLLSVFAGI TMFGPWGIII GPVLMILIVT TIDVYLAVYK GVELEQFEAP
     PVRRRWLPRR GPATSRNAPP PSTAE