ID   Y1101_MYCTU             Reviewed;         385 AA.
AC   P9WFM3; L0T7A7; O53449;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=Putative transport protein Rv1101c;
GN   OrderedLocusNames=Rv1101c; ORFNames=MTV017.54c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC       family. {ECO:0000305}.
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DR   EMBL; AL123456; CCP43854.1; -; Genomic_DNA.
DR   PIR; C70897; C70897.
DR   RefSeq; NP_215617.1; NC_000962.3.
DR   RefSeq; WP_003898727.1; NZ_NVQJ01000021.1.
DR   AlphaFoldDB; P9WFM3; -.
DR   STRING; 83332.Rv1101c; -.
DR   PaxDb; P9WFM3; -.
DR   DNASU; 885482; -.
DR   GeneID; 45425075; -.
DR   GeneID; 885482; -.
DR   KEGG; mtu:Rv1101c; -.
DR   TubercuList; Rv1101c; -.
DR   eggNOG; COG0628; Bacteria.
DR   OMA; CFWVVQP; -.
DR   PhylomeDB; P9WFM3; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; HDA:MTBBASE.
DR   InterPro; IPR002549; AI-2E-like.
DR   PANTHER; PTHR21716; PTHR21716; 1.
DR   Pfam; PF01594; AI-2E_transport; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..385
FT                   /note="Putative transport protein Rv1101c"
FT                   /id="PRO_0000148318"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        66..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        159..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        218..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        241..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        263..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        319..339
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   385 AA;  41717 MW;  7468D37557C66B10 CRC64;
     MNTEFTLTQK RALAILTLIA LLFGAYFLRN YFVLIVVAAV GAYLFTPLFK WFTKRFNTGL
     SAACTLLSAL AAVVVPVGAL VGLAIVQIAR MVDSVADWVR TTDLSTLGDK ILQFVNGLFD
     RVPFLHITVT ADALRKAMIS VAQNVGEWLL HFLRDAAGSL AGVITSAIIF VYVFVALLVN
     REKLRTLIGQ LNPLGEDVTD LYLQKMGSMV RGTVNGQFVI AACQGVAGAA SIYIAGFHHG
     FFIFAIVLTA LSIIPLGGGI VTIPFGIGMI FYGNIAGGIF VLLWHLLVVT NIDNVLRPIL
     VPRDARLNSA LMLLSVFAGI TMFGPWGIII GPVLMILIVT TIDVYLAVYK GVELEQFEAP
     PVRRRWLPRR GPATSRNAPP PSTAE