ID   Y1102_SACEN             Reviewed;         962 AA.
AC   A4F8Q9;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   17-APR-2007, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=UPF0182 protein SACE_1102 {ECO:0000255|HAMAP-Rule:MF_01600};
GN   OrderedLocusNames=SACE_1102;
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS   NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Saccharopolyspora.
OX   NCBI_TaxID=405948;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL
RC   2338;
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA   Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01600};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01600}.
CC   -!- SIMILARITY: Belongs to the UPF0182 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01600}.
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DR   EMBL; AM420293; CAM00434.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4F8Q9; -.
DR   SMR; A4F8Q9; -.
DR   STRING; 405948.SACE_1102; -.
DR   EnsemblBacteria; CAM00434; CAM00434; SACE_1102.
DR   KEGG; sen:SACE_1102; -.
DR   eggNOG; COG1615; Bacteria.
DR   HOGENOM; CLU_007733_1_0_11; -.
DR   OMA; HLRYPQD; -.
DR   Proteomes; UP000006728; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01600; UPF0182; 1.
DR   InterPro; IPR005372; UPF0182.
DR   PANTHER; PTHR39344; PTHR39344; 1.
DR   Pfam; PF03699; UPF0182; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..962
FT                   /note="UPF0182 protein SACE_1102"
FT                   /id="PRO_0000291293"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        55..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        168..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        203..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        250..270
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        279..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   REGION          707..730
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          876..916
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        891..909
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   962 AA;  105734 MW;  E5052A07CADDD151 CRC64;
     MPKLSRRSRI LLILGGVVLI ALIAGSRLLG TYVDWLWFGE VGRRQVFATQ VFSRLGLGVA
     AGAFVGVVLL LNLWIAYRSR PVFVPVSGPD DPLARYRTVA TERSRLFGWG IPIVIAVIAG
     LTAQSDWQTL QLFLHSVPFG QVDPEFGNDI SFYTFQLPFW RFLLSWSFVA ITVGFIGALV
     THYIFGGIRL AGRSGQVAAP ARIQLSVLAG LFVLLKAVDY FLDRYDLLLS DRNSLFTGAT
     YTDLNALMPV KLILMIIAVF CALAFFAAIF LRNLQIPAIA TVLLVLSSIL VGSVWPALLE
     QFSVRPNANQ REALSIERNL AATRSAFGIG ADKVTIKDYP GKTALTPGEV ADDEGTIPNI
     RLLDPNVLSD TFTQLTQQYN FYGFNEKLDV DRYREPNGQL RDYLVALREI DTDGLAQNQQ
     SWINRHMVYT HGNGFIAAPA DRVDSTFQEG ATQGGYPVFQ ISDVANGGKG AIPVDNPRVY
     YGELLNQNDY AIVGGNPGEA PREYDTDRSA YTYAGKGGVP LGSFFNRLVF AGYYGERNFL
     FNTAIGSDSK IMYERNPRDR VQKVAPWLKL DGDPYPAVVD GKVKWIIDGY TTLDNYPYSQ
     QTQFGQATTD TLTGVERQPN QPINYIRNSV KATVDAYDGS VDLYAVDEKD PVLKAWQGVF
     PGVVKPAKEI SPQLQEHFRY PEDLFKVQRQ LLTQYHVTNP GDFFSNRTFW EVPPDPTSSG
     QGGSNQGNQQ PPYYVLAQIE GQNQPTFQLT SALTALKRQN LAAWVSASSD PRDYGKLTVL
     RLPTDTQTPG PNQVQNQMES TPEVTENRTL FNNPQVTAIF GNLLTLPVAG GLLYVEPIYI
     QRNETESYPQ LARVLVSFGG KVGFSETLAG ALEQVFGPGA GQTAGDEPPP GQDSNQPPGQ
     QPPTQQPPAG SPEMTKAVAD IRTALESVRS AQQSGNFGRL GAAYQQLDEA LKRFEQLGGT
     GG