ID   Y1111_HALSA             Reviewed;         370 AA.
AC   P17103; Q9HQL0;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=Uncharacterized GTP-binding protein VNG_1111G;
GN   OrderedLocusNames=VNG_1111G;
OS   Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS   (Halobacterium halobium).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=64091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 33170 / DSM 669 / NCCB 81095 / NRC 34001;
RX   PubMed=2743981; DOI=10.1002/j.1460-2075.1989.tb03496.x;
RA   Shimmin L.C., Dennis P.P.;
RT   "Characterization of the L11, L1, L10 and L12 equivalent ribosomal protein
RT   gene cluster of the halophilic archaebacterium Halobacterium cutirubrum.";
RL   EMBO J. 8:1225-1235(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX   PubMed=11016950; DOI=10.1073/pnas.190337797;
RA   Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA   Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA   Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA   Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA   Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA   Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA   Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA   DasSarma S.;
RT   "Genome sequence of Halobacterium species NRC-1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC   -!- SIMILARITY: Belongs to the TRAFAC class OBG-HflX-like GTPase
CC       superfamily. OBG GTPase family. {ECO:0000255|PROSITE-ProRule:PRU01047}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X15078; CAA33176.1; -; Genomic_DNA.
DR   EMBL; AE004437; AAG19503.1; -; Genomic_DNA.
DR   PIR; C84267; C84267.
DR   PIR; S04116; QQHS4C.
DR   RefSeq; WP_010902798.1; NC_002607.1.
DR   AlphaFoldDB; P17103; -.
DR   SMR; P17103; -.
DR   STRING; 64091.VNG_1111G; -.
DR   PaxDb; P17103; -.
DR   PRIDE; P17103; -.
DR   EnsemblBacteria; AAG19503; AAG19503; VNG_1111G.
DR   GeneID; 5952835; -.
DR   GeneID; 62886625; -.
DR   KEGG; hal:VNG_1111G; -.
DR   PATRIC; fig|64091.14.peg.849; -.
DR   HOGENOM; CLU_044997_0_0_2; -.
DR   InParanoid; P17103; -.
DR   OMA; SAKHPGQ; -.
DR   OrthoDB; 21317at2157; -.
DR   PhylomeDB; P17103; -.
DR   Proteomes; UP000000554; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005525; F:GTP binding; IBA:GO_Central.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR   CDD; cd01896; DRG; 1.
DR   Gene3D; 3.10.20.30; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR012675; Beta-grasp_dom_sf.
DR   InterPro; IPR045001; DRG.
DR   InterPro; IPR031167; G_OBG.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR031662; GTP-binding_2.
DR   InterPro; IPR006074; GTP1-OBG_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR004095; TGS.
DR   InterPro; IPR012676; TGS-like.
DR   PANTHER; PTHR43127; PTHR43127; 1.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   Pfam; PF16897; MMR_HSR1_Xtn; 1.
DR   Pfam; PF02824; TGS; 1.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF81271; SSF81271; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51710; G_OBG; 1.
DR   PROSITE; PS00905; GTP1_OBG; 1.
DR   PROSITE; PS51880; TGS; 1.
PE   3: Inferred from homology;
KW   GTP-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..370
FT                   /note="Uncharacterized GTP-binding protein VNG_1111G"
FT                   /id="PRO_0000205443"
FT   DOMAIN          62..293
FT                   /note="OBG-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
FT   DOMAIN          293..368
FT                   /note="TGS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01228"
FT   BINDING         68..75
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
FT   BINDING         114..118
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
FT   BINDING         243..246
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
SQ   SEQUENCE   370 AA;  40329 MW;  CE4DD00A8FB1C259 CRC64;
     MGLEEDIESL EEEIANTPYN KSTEAHIGRL KAKLAEQKEK LEAQQSGSGG GGGYAVEQHG
     DATVALVGFP SVGKSSLINA MTNADSEVGA YEFTTLNVNP GMLEYRGANI QLLDVPGLIE
     GAAGGRGGGK EILSVIRGAD LVIFVLSAFE IEQYDRLAEE LYNVNIRVDA EPPSVTVRRK
     GKDGIDVNTS GELELDSDTV KGILRERGFI NANVTIRGNP SVDRLIDGVM DNRVYMPSLV
     TVNKVDLIEP SYAGTMKDAL RDHGVSPDDA IFISAAEEKG LDVLKERMWR ALGLIRIYMD
     KPGRGVDREE PLIIRRGETV DDAVQKLGGT LDERFRFARV TGPSAQHDDQ QVGRDHVLED
     EDVLRVVARR