Y1114_MYCBO
ID Y1114_MYCBO Reviewed; 242 AA.
AC P67158; A0A1R3XY99; O53433; X2BH03;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 25-MAY-2022, entry version 89.
DE RecName: Full=UPF0073 membrane protein Mb1114c;
GN OrderedLocusNames=BQ2027_MB1114C;
OS Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=233413;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT "The complete genome sequence of Mycobacterium bovis.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA Robbe-Austerman S., Gordon S.V.;
RT "Updated reference genome sequence and annotation of Mycobacterium bovis
RT AF2122/97.";
RL Genome Announc. 5:E00157-E00157(2017).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the UPF0073 (Hly-III) family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LT708304; SIT99713.1; -; Genomic_DNA.
DR RefSeq; NP_854769.1; NC_002945.3.
DR RefSeq; WP_003901993.1; NC_002945.4.
DR AlphaFoldDB; P67158; -.
DR SMR; P67158; -.
DR EnsemblBacteria; SIT99713; SIT99713; BQ2027_MB1114C.
DR GeneID; 45425058; -.
DR PATRIC; fig|233413.5.peg.1216; -.
DR OMA; HEVFHSL; -.
DR Proteomes; UP000001419; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0019835; P:cytolysis; IEA:InterPro.
DR InterPro; IPR004254; AdipoR/HlyIII-related.
DR InterPro; IPR005744; Hy-lIII.
DR PANTHER; PTHR20855; PTHR20855; 1.
DR Pfam; PF03006; HlyIII; 1.
DR TIGRFAMs; TIGR01065; hlyIII; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..242
FT /note="UPF0073 membrane protein Mb1114c"
FT /id="PRO_0000176903"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 108..128
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 186..206
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 222..242
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 242 AA; 26034 MW; BBC1DE12CF8D3500 CRC64;
MSGQADTATT AEARTPAHAA HHLVEGVARV LTKPRFRGWI HVYSAGTAVL AGASLVAVSW
AVGSAKAGLT TLAYTAATIT MFTVSATYHR VNWKSATARN WMKRADHSMI FVFIAGSYTP
FALLALPAHD GRVVLSIVWG GAIAGILLKM CWPAAPRSVG VPLYLLLGWV AVWYTATILH
NAGVTALVLL FVGGALYSIG GILYAVRWPD PWPTTFGYHE FFHACTAVAA ICHYIAMWFV
VF
