ID   Y1117_AERPE             Reviewed;         242 AA.
AC   Q9YCZ5;
DT   18-OCT-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=UPF0173 metal-dependent hydrolase APE_1117 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=APE_1117;
OS   Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 /
OS   K1).
OC   Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales;
OC   Desulfurococcaceae; Aeropyrum.
OX   NCBI_TaxID=272557;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1;
RX   PubMed=10382966; DOI=10.1093/dnares/6.2.83;
RA   Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K.,
RA   Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A.,
RA   Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S.,
RA   Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A.,
RA   Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H.;
RT   "Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon,
RT   Aeropyrum pernix K1.";
RL   DNA Res. 6:83-101(1999).
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
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DR   EMBL; BA000002; BAA80102.1; -; Genomic_DNA.
DR   PIR; F72712; F72712.
DR   AlphaFoldDB; Q9YCZ5; -.
DR   SMR; Q9YCZ5; -.
DR   STRING; 272557.APE_1117; -.
DR   EnsemblBacteria; BAA80102; BAA80102; APE_1117.
DR   KEGG; ape:APE_1117; -.
DR   eggNOG; arCOG00497; Archaea.
DR   OMA; WHGHSTW; -.
DR   Proteomes; UP000002518; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..242
FT                   /note="UPF0173 metal-dependent hydrolase APE_1117"
FT                   /id="PRO_0000156390"
SQ   SEQUENCE   242 AA;  25886 MW;  3ABAB6D247FE73F4 CRC64;
     MARLTYLGHA AFQLEAGGRK ILVDPWLSNP KSPVKPEEVE GVDLIVITHS HFDHLGDVGK
     IAAKNPGAKV LAVYEVADLA AEEIAKETGA SKDELFNAGR VIGANIGGPV VLQDLGLKVA
     FTPATHSSVG VAAGAVIITG EGRVYHAGDT GVTMDMRLVG EIYKPHVALL PIGGHFTMDP
     VEAAKAVELI RPLVAIPMHY GTFPVLYGDP EEFKKRVEEK CLPTQVRILK PGESYEFDFS
     KA