CAPP_TOLAT
ID CAPP_TOLAT Reviewed; 877 AA.
AC C4L7S3;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 07-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 55.
DE RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000255|HAMAP-Rule:MF_00595};
DE Short=PEPC {ECO:0000255|HAMAP-Rule:MF_00595};
DE Short=PEPCase {ECO:0000255|HAMAP-Rule:MF_00595};
DE EC=4.1.1.31 {ECO:0000255|HAMAP-Rule:MF_00595};
GN Name=ppc {ECO:0000255|HAMAP-Rule:MF_00595}; OrderedLocusNames=Tola_0092;
OS Tolumonas auensis (strain DSM 9187 / TA4).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Tolumonas.
OX NCBI_TaxID=595494;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 9187 / TA4;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Spring S.,
RA Beller H.;
RT "Complete sequence of Tolumonas auensis DSM 9187.";
RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC for the tricarboxylic acid cycle. {ECO:0000255|HAMAP-Rule:MF_00595}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00595};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00595};
CC -!- SIMILARITY: Belongs to the PEPCase type 1 family. {ECO:0000255|HAMAP-
CC Rule:MF_00595}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001616; ACQ91722.1; -; Genomic_DNA.
DR RefSeq; WP_012728322.1; NC_012691.1.
DR AlphaFoldDB; C4L7S3; -.
DR SMR; C4L7S3; -.
DR STRING; 595494.Tola_0092; -.
DR EnsemblBacteria; ACQ91722; ACQ91722; Tola_0092.
DR KEGG; tau:Tola_0092; -.
DR eggNOG; COG2352; Bacteria.
DR HOGENOM; CLU_006557_2_0_6; -.
DR OMA; PWVFGWT; -.
DR OrthoDB; 398146at2; -.
DR Proteomes; UP000009073; Chromosome.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR HAMAP; MF_00595; PEPcase_type1; 1.
DR InterPro; IPR021135; PEP_COase.
DR InterPro; IPR022805; PEP_COase_bac/pln-type.
DR InterPro; IPR018129; PEP_COase_Lys_AS.
DR InterPro; IPR033129; PEPCASE_His_AS.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR PANTHER; PTHR30523; PTHR30523; 1.
DR Pfam; PF00311; PEPcase; 1.
DR PRINTS; PR00150; PEPCARBXLASE.
DR SUPFAM; SSF51621; SSF51621; 1.
DR PROSITE; PS00781; PEPCASE_1; 1.
DR PROSITE; PS00393; PEPCASE_2; 1.
PE 3: Inferred from homology;
KW Carbon dioxide fixation; Lyase; Magnesium; Reference proteome.
FT CHAIN 1..877
FT /note="Phosphoenolpyruvate carboxylase"
FT /id="PRO_1000212179"
FT ACT_SITE 137
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00595"
FT ACT_SITE 542
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00595"
SQ SEQUENCE 877 AA; 100151 MW; 60CCEC8434EA39CC CRC64;
MNDMYAALRG NVGMLGHLLG KTIKEHLGDE FLDKIENIRQ LAKSSRQGNE EDRQKLITTL
KNLSDDELLP VARAFSQFLN LANVAEQFHS MSRQGELHTT LDPLDSLFDK LKNANLSEQE
IIDTVCELDI ELVLTAHPTE VTRRTLIHKH VQLNECLEEL ELQDLTPREC KFIQHRIEQL
VNQSWHTNEI REQRPTPVDE AKWGFAVIEN NLWPAIPLFL RQLDDRLQEN FGIRLPLRAH
PVRIASWMGG DRDGNPFVTA KVTQEVLLLS RWVAINLFLT DIQELVSELS MTDCNEELRQ
RVGECSEPYR AILRVVRDSL RETQQAVTAK LQGQYTENRD LITRTEQLRE PLELCYRSLQ
SCGMSIIADG MLLDVLRKLA CFGVNLLKLD IRQDGERHGQ VLSELTQYLE LGDYAEWRET
EKQEFLLKEL ASRRPLLPAN WQPSAESQEV VDTCRVIAQT DPDAFGIYII SMARQPSDVL
AVQLLLKEVG CKFHMPIAPL FETQNDLQNA AAVLNRLLSV EWYRNYIRGQ QYVMIGYSDS
AKDAGMMSAG WAQYRAMEDL VAIAEREDLK LTLFHGRGGT IGRGGGPAHQ AILSQPPGSL
KGGFRVTEQG EMIRFKFGLP EVAIHNFKLY TSAVLEANLL PPPKPEAAWY DVMDKLSEIS
CQHYRSIVRD EPDFVPYFRA ATPEMELGKL PLGSRPSKRK PNGGVESLRA IPWIFAWTQN
RLMLPSWLGA HVALQAVMDE GKEDLLKEMD QQWPFFHTRL EMLEMVFLKA DLWLAEYYDL
RLAPENLWPL GKRLRQELQD SINVVLQLLP KRGELLDDQP WIKESIKLRN PYTDPLNVLQ
VELLHRSRAT PDEVNPQVDQ ALMVTIAGIA AGMRNTG