ID   Y1124_NEIMB             Reviewed;         215 AA.
AC   Q7DDE8;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Putative lipoprotein NMB1124/NMB1162;
DE   Flags: Precursor;
GN   OrderedLocusNames=NMB1124;
GN   and
GN   OrderedLocusNames=NMB1162;
OS   Neisseria meningitidis serogroup B (strain MC58).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=122586;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MC58;
RX   PubMed=10710307; DOI=10.1126/science.287.5459.1809;
RA   Tettelin H., Saunders N.J., Heidelberg J.F., Jeffries A.C., Nelson K.E.,
RA   Eisen J.A., Ketchum K.A., Hood D.W., Peden J.F., Dodson R.J., Nelson W.C.,
RA   Gwinn M.L., DeBoy R.T., Peterson J.D., Hickey E.K., Haft D.H.,
RA   Salzberg S.L., White O., Fleischmann R.D., Dougherty B.A., Mason T.M.,
RA   Ciecko A., Parksey D.S., Blair E., Cittone H., Clark E.B., Cotton M.D.,
RA   Utterback T.R., Khouri H.M., Qin H., Vamathevan J.J., Gill J., Scarlato V.,
RA   Masignani V., Pizza M., Grandi G., Sun L., Smith H.O., Fraser C.M.,
RA   Moxon E.R., Rappuoli R., Venter J.C.;
RT   "Complete genome sequence of Neisseria meningitidis serogroup B strain
RT   MC58.";
RL   Science 287:1809-1815(2000).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=NZ98/254 / Serogroup B;
RX   PubMed=16645985; DOI=10.1002/pmic.200500821;
RA   Vipond C., Suker J., Jones C., Tang C., Feavers I.M., Wheeler J.X.;
RT   "Proteomic analysis of a meningococcal outer membrane vesicle vaccine
RT   prepared from the group B strain NZ98/254.";
RL   Proteomics 6:3400-3413(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- MISCELLANEOUS: Present in outer membrane vesicle formulations which are
CC       used as vaccines in human.
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DR   EMBL; AE002098; AAF41512.1; -; Genomic_DNA.
DR   EMBL; AE002098; AAF41547.1; -; Genomic_DNA.
DR   RefSeq; NP_274153.1; NC_003112.2.
DR   RefSeq; NP_274189.1; NC_003112.2.
DR   RefSeq; WP_002217218.1; NC_003112.2.
DR   AlphaFoldDB; Q7DDE8; -.
DR   SMR; Q7DDE8; -.
DR   STRING; 122586.NMB1124; -.
DR   PaxDb; Q7DDE8; -.
DR   EnsemblBacteria; AAF41512; AAF41512; NMB1124.
DR   EnsemblBacteria; AAF41547; AAF41547; NMB1162.
DR   GeneID; 61281336; -.
DR   KEGG; nme:NMB1124; -.
DR   KEGG; nme:NMB1162; -.
DR   PATRIC; fig|122586.8.peg.1426; -.
DR   HOGENOM; CLU_097432_1_0_4; -.
DR   OMA; EAGYYVM; -.
DR   Proteomes; UP000000425; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008517; DUF799.
DR   Pfam; PF05643; DUF799; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           17..215
FT                   /note="Putative lipoprotein NMB1124/NMB1162"
FT                   /id="PRO_0000320331"
FT   LIPID           17
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           17
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   215 AA;  22931 MW;  B963F5F9ED8A53F2 CRC64;
     MKPLILGLAA VLALSACQVQ KAPDFDYTSF KESKPASILV VPPLNESPDV NGTWGVLAST
     AAPLSEAGYY VFPAAVVEET FKQNGLTNAA DIHAVRPEKL HQIFGNDAVL YITVTEYGTS
     YQILDSVTTV SAKARLVDSR NGKELWSGSA SIREGSNNSN SGLLGALVSA VVNQIANSLT
     DRGYQVSKTA AYNLLSPYSH NGILKGPRFV EEQPK