ID   Y1126_NEIMB             Reviewed;         223 AA.
AC   Q7DDH4;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Putative lipoprotein NMB1126/NMB1164;
DE   Flags: Precursor;
GN   OrderedLocusNames=NMB1126;
GN   and
GN   OrderedLocusNames=NMB1164;
OS   Neisseria meningitidis serogroup B (strain MC58).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=122586;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MC58;
RX   PubMed=10710307; DOI=10.1126/science.287.5459.1809;
RA   Tettelin H., Saunders N.J., Heidelberg J.F., Jeffries A.C., Nelson K.E.,
RA   Eisen J.A., Ketchum K.A., Hood D.W., Peden J.F., Dodson R.J., Nelson W.C.,
RA   Gwinn M.L., DeBoy R.T., Peterson J.D., Hickey E.K., Haft D.H.,
RA   Salzberg S.L., White O., Fleischmann R.D., Dougherty B.A., Mason T.M.,
RA   Ciecko A., Parksey D.S., Blair E., Cittone H., Clark E.B., Cotton M.D.,
RA   Utterback T.R., Khouri H.M., Qin H., Vamathevan J.J., Gill J., Scarlato V.,
RA   Masignani V., Pizza M., Grandi G., Sun L., Smith H.O., Fraser C.M.,
RA   Moxon E.R., Rappuoli R., Venter J.C.;
RT   "Complete genome sequence of Neisseria meningitidis serogroup B strain
RT   MC58.";
RL   Science 287:1809-1815(2000).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=17038831; DOI=10.4161/hv.1.2.1651;
RA   Vipond C., Wheeler J.X., Jones C., Feavers I.M., Suker J.;
RT   "Characterization of the protein content of a meningococcal outer membrane
RT   vesicle vaccine by polyacrylamide gel electrophoresis and mass
RT   spectrometry.";
RL   Hum. Vaccin. 1:80-84(2005).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=NZ98/254 / Serogroup B;
RX   PubMed=16645985; DOI=10.1002/pmic.200500821;
RA   Vipond C., Suker J., Jones C., Tang C., Feavers I.M., Wheeler J.X.;
RT   "Proteomic analysis of a meningococcal outer membrane vesicle vaccine
RT   prepared from the group B strain NZ98/254.";
RL   Proteomics 6:3400-3413(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- MISCELLANEOUS: Present in outer membrane vesicle formulations which are
CC       used as vaccines in human.
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DR   EMBL; AE002098; AAF41514.1; -; Genomic_DNA.
DR   EMBL; AE002098; AAF41549.1; -; Genomic_DNA.
DR   PIR; F81120; F81120.
DR   RefSeq; NP_274155.1; NC_003112.2.
DR   RefSeq; NP_274191.1; NC_003112.2.
DR   RefSeq; WP_002217215.1; NC_003112.2.
DR   AlphaFoldDB; Q7DDH4; -.
DR   SMR; Q7DDH4; -.
DR   STRING; 122586.NMB1126; -.
DR   PaxDb; Q7DDH4; -.
DR   PRIDE; Q7DDH4; -.
DR   EnsemblBacteria; AAF41514; AAF41514; NMB1126.
DR   EnsemblBacteria; AAF41549; AAF41549; NMB1164.
DR   GeneID; 61281338; -.
DR   KEGG; nme:NMB1126; -.
DR   KEGG; nme:NMB1164; -.
DR   PATRIC; fig|122586.8.peg.1428; -.
DR   HOGENOM; CLU_074310_1_0_4; -.
DR   OMA; IGKFDNR; -.
DR   Proteomes; UP000000425; Chromosome.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR005534; Curli_assmbl/transp-comp_CsgG.
DR   Pfam; PF03783; CsgG; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           20..223
FT                   /note="Putative lipoprotein NMB1126/NMB1164"
FT                   /id="PRO_0000320332"
FT   LIPID           20
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           20
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   223 AA;  23798 MW;  2AB27B742CAAB7F0 CRC64;
     MKTVSTAVVL AAAAVSLTGC ATESSRSLEV EKVASYNTQY HGVRTPISVG TFDNRSSFQK
     GIFSDGEDRL GSQAKTILVT HLQQTNRFNV LNRTNLNALK QESGISGKAH NLKGADYVVT
     GDVTEFGRRD VGDHQLFGIL GRGKSQIAYA KVALNIVNVN TSEIVYSAQG AGEYALSNRE
     IIGFGGTSGY DATLNGKVLD LAIREAVNSL VQAVDNGAWQ PNR