ID   Y1143_METST             Reviewed;         350 AA.
AC   Q2NF79;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 2.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Putative HTH-type transcriptional regulatory protein Msp_1143 {ECO:0000255|HAMAP-Rule:MF_00584};
GN   OrderedLocusNames=Msp_1143;
OS   Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 /
OS   MCB-3).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanosphaera.
OX   NCBI_TaxID=339860;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3;
RX   PubMed=16385054; DOI=10.1128/jb.188.2.642-658.2006;
RA   Fricke W.F., Seedorf H., Henne A., Kruer M., Liesegang H., Hedderich R.,
RA   Gottschalk G., Thauer R.K.;
RT   "The genome sequence of Methanosphaera stadtmanae reveals why this human
RT   intestinal archaeon is restricted to methanol and H2 for methane formation
RT   and ATP synthesis.";
RL   J. Bacteriol. 188:642-658(2006).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABC57524.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000102; ABC57524.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; Q2NF79; -.
DR   SMR; Q2NF79; -.
DR   STRING; 339860.Msp_1143; -.
DR   EnsemblBacteria; ABC57524; ABC57524; Msp_1143.
DR   KEGG; mst:Msp_1143; -.
DR   eggNOG; arCOG04152; Archaea.
DR   HOGENOM; CLU_075726_0_0_2; -.
DR   Proteomes; UP000001931; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   HAMAP; MF_00584; HTH_type_cro_C1; 1.
DR   InterPro; IPR020886; Arc_TR_HTH.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   Pfam; PF01381; HTH_3; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..350
FT                   /note="Putative HTH-type transcriptional regulatory protein
FT                   Msp_1143"
FT                   /id="PRO_0000259360"
FT   DOMAIN          135..189
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
FT   DNA_BIND        146..165
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
SQ   SEQUENCE   350 AA;  40399 MW;  9D625749B1A63DE6 CRC64;
     MDSSTITRKN ILDDVTSLLT SFGFKTSNIY DRNCFDLLAR KKDILIILKI LVNIDSLTPT
     QAEELSKISG TFLASPIIIG YKSKHNYLEE DIVYERHEIP VISPQTLCNI IVNDIHPEIF
     AKRGGYYVKI NGNLLKNLRE KNNLSLKELA DISHVSRETI YKYEKGNSQT YPETAMMLEQ
     VLNSPITESI NLLETNNTKT TTLDKKIQEP IELIKLGYDI KSSNKAPFDA ISERQEETEE
     VRQLKEKLES KLDEIEKIRA EINKKTKHHN LLITNMERNR SDNTLNKIAN CTEDISLITG
     HDALFVLEHK KDKEFIKKIP AIYTWELKNM DNMEELLKLI KERKEEANDS